000 04099nam a22004935i 4500
001 978-94-007-1451-9
003 DE-He213
005 20140220083833.0
007 cr nn 008mamaa
008 110707s2011 ne | s |||| 0|eng d
020 _a9789400714519
_9978-94-007-1451-9
024 7 _a10.1007/978-94-007-1451-9
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aBerenson, Gerald S.
_eeditor.
245 1 0 _aEvolution of Cardio-Metabolic Risk from Birth to Middle Age:
_h[electronic resource] :
_bThe Bogalusa Heart Study /
_cedited by Gerald S. Berenson.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2011.
300 _aXIII, 210p. 54 illus., 10 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aForeword -- Preface -- 1. Exploring Chromosomal Leukocyte Telomere Length Dynamics in the Bogalusa Heart Study -- 2. Fetal Origins of Variables Related to Cardio-metabolic Risk -- 3. Trajectories of Variables Related to Cardio-metabolic Risk since Childhood -- 4. Evolution of Metabolic Syndrome from Childhood -- 5. Black-white Divergence in Impaired Fasting Glucose and Type 2 Diabetes Mellitus -- 6. Birth Weight, Stimulus Response and Hemodynamic Variability Implicate Racial (black-white) Contrasts of Autonomic Control of Heart Rate and Blood Pressure and Related Cardiovascular Disease -- 7. Obesity  - Findings from the Bogalusa Heart Study -- 8. Morbid Obesity and Premature Death in the Young -- 9. Target Organ Damage Related to Cardiovascular Risk Factors in Youth -- 10. The Cardiovascular Risk in Young Finns Study and the Special Turku Coronary Risk Factor Intervention Project (STRIP) -- 11. Prevention of Heart Disease in Childhood – Rationale for Primordial Prevention -- 12. Dietary Intake of  Children over Two Decades in a Community and an Approach for Modification -- 13. Cardiovascular Health Promotion - Physical Fitness in the School Setting -- 14. Primordial Prevention through School Health Promotion.
520 _aThat precursors of adult coronary artery disease, hypertension, and type II diabetes begin in childhood have been clearly established by the Bogalusa Heart Study. This unique research program has been able to follow a biracial (black/white) population over 35 years from childhood through mid-adulthood to provide perspectives on the natural history of adult heart diseases. Not only do these observations describe trajectories of cardio-metabolic risk variables leading to these diseases but provide a rationale for the need to begin prevention beginning in childhood. The trajectories of the burden of cardio-metabolic risk variables in the context of their fetal origin and chromosome telomere dynamics provide some insight into the metabolic imprinting in utero and aging process. The observed racial contrasts on cardio-metabolic risk variables implicate various biologic pathways interacting with environment contributing to the high morbidity and mortality from related diseases in our population. To address the seriousness of the onset of cardiovascular disease in youth, approaches to primordial prevention are described focussing on childhood health education as an important aspect of Preventive Cardiology.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aGeriatrics.
650 0 _aPublic health.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aMedicine/Public Health, general.
650 2 4 _aHuman Physiology.
650 2 4 _aGeriatrics/Gerontology.
650 2 4 _aPublic Health.
650 2 4 _aHealth Promotion and Disease Prevention.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400714502
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-1451-9
912 _aZDB-2-SBL
999 _c109487
_d109487