000			02930nam a22004815i 4500
001			978-94-007-0428-2
003			DE-He213
005			20140220083829.0
007			cr nn 008mamaa
008			110301s2011 ne | s |||| 0|eng d
020			_a9789400704282 _9978-94-007-0428-2
024	7		_a10.1007/978-94-007-0428-2 _2doi
050		4	_aR-RZ
072		7	_aMBGR _2bicssc
072		7	_aMED000000 _2bisacsh
082	0	4	_a610 _223
100	1		_aBanfalvi, Gaspar. _eeditor.
245	1	0	_aCellular Effects of Heavy Metals _h[electronic resource] / _cedited by Gaspar Banfalvi.
264		1	_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2011.
300			_aXIV, 348p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
520			_aThe term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organismal level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mecha nisms such as gene expression, protein folding, stress signalling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.
650		0	_aMedicine.
650		0	_aChemistry, inorganic.
650		0	_aCytology.
650		0	_aEnvironmental toxicology.
650	1	4	_aBiomedicine.
650	2	4	_aBiomedicine general.
650	2	4	_aCell Biology.
650	2	4	_aOxidative Stress.
650	2	4	_aApoptosis.
650	2	4	_aEcotoxicology.
650	2	4	_aInorganic Chemistry.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789400704275
856	4	0	_uhttp://dx.doi.org/10.1007/978-94-007-0428-2
912			_aZDB-2-SBL
999			_c109285 _d109285