000			03064nam a22005055i 4500
001			978-3-642-16833-8
003			DE-He213
005			20140220083750.0
007			cr nn 008mamaa
008			110418s2011 gw | s |||| 0|eng d
020			_a9783642168338 _9978-3-642-16833-8
024	7		_a10.1007/978-3-642-16833-8 _2doi
050		4	_aQH573-671
072		7	_aPSF _2bicssc
072		7	_aSCI049000 _2bisacsh
082	0	4	_a571.6 _223
100	1		_aPavão, Mauro S.G. _eeditor.
245	1	0	_aGlycans in Diseases and Therapeutics _h[electronic resource] / _cedited by Mauro S.G. Pavão.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2011.
300			_aXII, 188 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aBiology of Extracellular Matrix
505	0		_aHeparan Sulfate Proteoglycan in Inflammation and Angiogenesis -- Heparan Sulfate Proteoglycans in Infection -- Glycans in cancer -- Glycosaminoglycans in atherosclerosis and thrombosis -- Glycans in Embryonic Stem Cells -- Heparan sulfate proteoglycans in cancer progression and therapy -- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.
520			_aInitially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
650		0	_aLife sciences.
650		0	_aHuman physiology.
650		0	_aMedicine.
650		0	_aBiochemistry.
650		0	_aCytology.
650	1	4	_aLife Sciences.
650	2	4	_aCell Biology.
650	2	4	_aAnimal Biochemistry.
650	2	4	_aMolecular Medicine.
650	2	4	_aHuman Physiology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642168321
830		0	_aBiology of Extracellular Matrix
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-16833-8
912			_aZDB-2-SBL
999			_c107205 _d107205