000 02939nam a22004575i 4500
001 978-3-642-03503-6
003 DE-He213
005 20140220083741.0
007 cr nn 008mamaa
008 110805s2011 gw | s |||| 0|eng d
020 _a9783642035036
_9978-3-642-03503-6
024 7 _a10.1007/978-3-642-03503-6
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
100 1 _aJankowski, Janusz A. Z.
_eeditor.
245 1 0 _aInflammation and Gastrointestinal Cancers
_h[electronic resource] /
_cedited by Janusz A. Z. Jankowski.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2011.
300 _aX, 202 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aRecent Results in Cancer Research,
_x0080-0015 ;
_v185
505 0 _aBasic concepts of inflammation and its role in carcinogenesis -- Inherited syndromes predisposing to inflammation and GI cancer -- Stem cell biology and mucosal inflammation -- Acid reflux and esophageal cancer -- H Pylori and gastric cancer -- Inflammatory bowel disease and colon cancer -- Liver cancer -- Current screening strategies -- Targeted drug therapies and cancer -- Genetics of inflammation in the GI tract and how it can cause cancer -- Endoscopic methods.
520 _aInflammation in gastrointestinal mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it has fundamental clinical consequences, the principal of which is premalignant metaplasia throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for GI cancer. This book discusses all aspects of the relation between inflammation and GI cancer, from the basic science through to the translational science which is helping in the optimization of clinical management strategies. Among the topics considered are the impact of inherited syndromes; the roles of acid reflux, H. pylori, inflammatory bowel disease, and primary sclerosing cholangitis; screening strategies; targeted drug therapies; genetics; and the use of endoscopic methods. The authors are the best in their field, and this book is designed for the enthusiastic student as well as the professional in GI science and medicine.
650 0 _aMedicine.
650 0 _aGastroenterology.
650 0 _aOncology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aGastroenterology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642035029
830 0 _aRecent Results in Cancer Research,
_x0080-0015 ;
_v185
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-03503-6
912 _aZDB-2-SME
999 _c106705
_d106705