000 04496nam a22005655i 4500
001 978-3-642-00818-4
003 DE-He213
005 20140220083741.0
007 cr nn 008mamaa
008 110210s2011 gw | s |||| 0|eng d
020 _a9783642008184
_9978-3-642-00818-4
024 7 _a10.1007/978-3-642-00818-4
_2doi
050 4 _aR895-920
072 7 _aMMPH
_2bicssc
072 7 _aMJN
_2bicssc
072 7 _aMED056000
_2bisacsh
072 7 _aMED008000
_2bisacsh
082 0 4 _a616.0757
_223
100 1 _aBarkhof, Frederik.
_eauthor.
245 1 0 _aNeuroimaging in Dementia
_h[electronic resource] /
_cby Frederik Barkhof, Nick C. Fox, António J. Bastos-Leite, Philip Scheltens.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2011.
300 _aXIX, 278 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aClinical background: Definition of dementia. Prevalence and incidence. Nosological approach. Differential diagnosis. Multi-disciplinary integration -- The toolbox: Structural imaging. Feature extraction. Advanced MR techniques. SPECT and PET -- Normal Ageing: Brain volume loss. Enlarged perivascular (Virchow-Robin) spaces and lacunes. Age-related white matter changes. Iron accumulation. Hidden age-related changes in brain tissue -- Primary gray matter loss: Alzheimer’s disease. Frontotemporal lobar degeneration. Dementia with Parkinsonism. Dementia in other movement disorders. Prion-linked dementias. Recreational drugs and alcohol -- Vascular Disease: history and nosology. Large vessel vascular dementia. Small vessel vascular dementia. Vasculitis. Systemic hypoxia. Mixed dementia and interrelationship VaD/AD -- Disorders mainly affecting white matter: Infections. Inflammatory disorders. Inborn errors of metabolism. Toxic leukencephalopathy and dementia. Post-therapy effect. Trauma -- Dementias with associated brain swelling. Giant VRS. Infections. Neoplastic disease and radiation necrosis. Auto-immune limbic encephalitis. Normal pressure hydrocephalus (NPH). Arteriovenous malformation (AVM) and fistula (AVF). Reversible posterior leukencephalopathy (RPLS). Anti-amyloid therapy.
520 _aAgainst a background of an ever-increasing number of patients, new management options, and novel imaging modalities, neuroimaging is playing an increasingly important role in the diagnosis of dementia.  This up-to-date, superbly illustrated book aims to provide a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the wide range of causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible.  After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key imaging findings in patients with dementias. A structured path of analysis follows the main presenting feature: disorders associated with primary gray matter loss, with white matter changes, with brain swelling, etc. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book should prove an invaluable resource.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aGeriatrics.
650 0 _aRadiology, Medical.
650 0 _aNuclear medicine.
650 0 _aNeurology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aNeuroradiology.
650 2 4 _aNeurology.
650 2 4 _aNuclear Medicine.
650 2 4 _aNeurosciences.
650 2 4 _aGeriatrics/Gerontology.
700 1 _aFox, Nick C.
_eauthor.
700 1 _aBastos-Leite, António J.
_eauthor.
700 1 _aScheltens, Philip.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642008177
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-00818-4
912 _aZDB-2-SME
999 _c106688
_d106688