000 03081nam a22004815i 4500
001 978-3-540-85772-3
003 DE-He213
005 20140220083740.0
007 cr nn 008mamaa
008 110420s2011 gw | s |||| 0|eng d
020 _a9783540857723
_9978-3-540-85772-3
024 7 _a10.1007/978-3-540-85772-3
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
100 1 _aMoehler, Thomas.
_eeditor.
245 1 0 _aMultiple Myeloma
_h[electronic resource] /
_cedited by Thomas Moehler, Hartmut Goldschmidt.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2011.
300 _aXXIV, 340 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aRecent Results in Cancer Research,
_x0080-0015 ;
_v183
505 0 _aHistory and epidemiology -- Pathophysiology: Molecular biology of plasma cell disorders. Alterations in microenvironment -- Clinical Features: Imaging. Integrated innovative approach for diagnosis and staging -- Therapy: High-dose chemotherapy and ABSCT -- Allogeneic transplantation. Novel Drugs -- Immunotherapeutic approaches -- First-line treatment and maintenance -- Relapse -- Radiotherapy -- Kyphoplasty -- Supportive Therapy -- Appendix: Staging and prognosis systems.
520 _aMultiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy. In particular, the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide means that multiple myeloma now stands at the forefront of advances in oncology drug development. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aHematology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aHematology.
650 2 4 _aCancer Research.
700 1 _aGoldschmidt, Hartmut.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540857716
830 0 _aRecent Results in Cancer Research,
_x0080-0015 ;
_v183
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-85772-3
912 _aZDB-2-SME
999 _c106664
_d106664