000			03631nam a22004935i 4500
001			978-1-61779-322-6
003			DE-He213
005			20140220083736.0
007			cr nn 008mamaa
008			110826s2011 xxu| s |||| 0|eng d
020			_a9781617793226 _9978-1-61779-322-6
024	7		_a10.1007/978-1-61779-322-6 _2doi
050		4	_aQH588.S83
072		7	_aPSAK _2bicssc
072		7	_aSCI017000 _2bisacsh
072		7	_aSCI049000 _2bisacsh
082	0	4	_a571.6 _223
100	1		_aBernstein, Harold S. _eeditor.
245	1	0	_aTissue Engineering in Regenerative Medicine _h[electronic resource] / _cedited by Harold S. Bernstein.
264		1	_aTotowa, NJ : _bHumana Press, _c2011.
300			_aXIV, 426 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aStem Cell Biology and Regenerative Medicine
505	0		_aHematopoietic Stem Cell Transplantation: Reflections on Yesterday and Thoughts for Tomorrow -- Human Embryonic Stem Cells in Regenerative Medicine -- Current Status of Induced Pluripotent Stem Cells -- Mesenchymal Stromal Cells: Latest Advances -- The Role of Mechanical Force in Guiding Tissue Differentiation -- Synthetic Multi-Level Matrices for Bone Regeneration -- Directing Cell Fate Through Biomaterial Microenvironments -- Basic Considerations with Cell Sheets -- Myocardial Repair and Restoration -- Skeletal Muscle Engineering: The Need for a Suitable Niche -- Restoring Blood Vessels -- Engineering Functional Bone Grafts -- Engineering Functional Cartilage Grafts -- Adult Stem Cells and Regeneration of Adipose Tissue -- Hollow Organ Engineering -- Engineering Complex Synthetic Organs -- Liver Regeneration and Tissue Engineering -- Immune Modulation for Stem Cell Therapy -- Regenerative Medicine and the Foreign Body Response -- Small Animal Models of Tissue Regeneration -- Use of Large Animal and Nonhuman Primate Models for Cell Therapy and Tissue Engineering.
520			_aOver the past decade, significant advances in the fields of stem cell biology, bioengineering, and animal models have converged on the discipline of regenerative medicine. This volume provides a state-of-the-art report on tissue engineering toward the goals of tissue and organ restoration and regeneration. Examples from different organ systems are used to illustrate progress with growth factors to assist in tissue remodeling; the capacity of stem cells for restoring damaged tissues; novel synthetic biomaterials to facilitate cell therapy; transplantable tissue patches that preserve three-dimensional structure; synthetic organs generated in culture; aspects of the immune response to transplanted cells and materials; and the development of suitable animal models for non-human clinical trials. Throughout the chapters, the reader will observe a common theme of basic discovery informing clinical translation, and clinical studies in animals and humans guiding subsequent experiments at the bench.
650		0	_aLife sciences.
650		0	_aBiotechnology.
650		0	_aCytology.
650		0	_aStem cells.
650	1	4	_aLife Sciences.
650	2	4	_aStem Cells.
650	2	4	_aCell Biology.
650	2	4	_aBiotechnology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781617793219
830		0	_aStem Cell Biology and Regenerative Medicine
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-61779-322-6
912			_aZDB-2-SBL
999			_c106419 _d106419