000 03241nam a22004455i 4500
001 978-1-60761-965-9
003 DE-He213
005 20140220083735.0
007 cr nn 008mamaa
008 101125s2011 xxu| s |||| 0|eng d
020 _a9781607619659
_9978-1-60761-965-9
024 7 _a10.1007/978-1-60761-965-9
_2doi
050 4 _aQH588.S83
072 7 _aPSAK
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aCharles, S.
_eeditor.
245 1 0 _aProgenitor Cell Therapy for Neurological Injury
_h[electronic resource] /
_cedited by S. Charles.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana Press,
_c2011.
300 _aX, 200 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStem Cell Biology and Regenerative Medicine
505 0 _aPreface -- Chapter 1. Basics of Stem and Progenitor Cells -- Chapter 2. Progenitor Cell Tissue Engineering: Scaffold Design and Fabrication -- Chapter 3. Stem Cell Delivery Methods and Routes -- Chapter 4. Neural Stem Cells-Endogenous Repair of Neurological Injury -- Chapter 5. Traumatic Brain Injury: Pathophysiology and Models -- Chapter 6. Traumatic Brain Injury: Relationship of Clinical Injury to Progenitor Cell Therapeutics -- Chapter 7. Cell-Based Therapy for Stroke -- Chapter 8. Spinal Cord Injury: Pathophysiology and Progenitor Cell Therapy -- Chapter 9. Current Status of Clinical Trials using Progenitor Cells for Neurological Injury.
520 _aThere are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke. Actually, most treatments are designed simply to limit secondary damage. However, pre-clinical data supports the idea that exogenous stem and progenitor cells have the potential to promote a reparative response to severe neurological injuries. Progenitor Cell Therapy for Neurological Injury is a compilation of seminal essays that explore many unique aspects of neurological injury, focusing on the critical translational issues of cell delivery. Specifically, it discusses routes of administration, types of progenitor cells (alone and/or in combinations), timing of delivery and adjuncts to promote cell engraftment, survival and effectiveness. In addition, many chapters address measuring the effects of transplanted cells and cell tracking. The paradigms of how cell-based therapeutics affect neurological injury is changing rapidly. The developments in this field may ultimately offer realistic hope for improvement in patients with severe injuries. This book is a vital key toward unlocking those future treatments.
650 0 _aLife sciences.
650 0 _aStem cells.
650 1 4 _aLife Sciences.
650 2 4 _aStem Cells.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781607619642
830 0 _aStem Cell Biology and Regenerative Medicine
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-60761-965-9
912 _aZDB-2-SBL
999 _c106380
_d106380