000 02726nam a22004215i 4500
001 978-1-4419-6694-0
003 DE-He213
005 20140220083721.0
007 cr nn 008mamaa
008 101029s2011 xxu| s |||| 0|eng d
020 _a9781441966940
_9978-1-4419-6694-0
024 7 _a10.1007/978-1-4419-6694-0
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aFitzgerald, Rebecca C.
_eeditor.
245 1 0 _aPre-Invasive Disease: Pathogenesis and Clinical Management
_h[electronic resource] /
_cedited by Rebecca C. Fitzgerald.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2011.
300 _aXXII, 519p. 78 illus., 68 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
520 _aThere are many books written on cancer, but this monograph focuses on pre-invasive disease. One of the prizes waiting to be won in cancer medicine is to thoroughly understand the processes by which a cell becomes invasive. This quest takes us into the world of stem cells and regulation of gene expression as well as to an understanding of the relative contribution of hereditary factors alongside exposures to environmental agents. This book explores these fundamental concepts as well as considering how advances in disease models combined with –omic technologies and molecular imaging might lead to advances in treatments such as chemoprevention and endoscopic treatments. The final section of the book takes nine specific examples of pre-invasive disease and explores the current state of knowledge and clinical practice as well as looking to the future. This book is written by International experts in their field and should appeal to students and seasoned researchers, to scientists and to clinicians. No prior knowledge of the topic is required to appreciate this text and yet the book charters new territory. New perspectives are given on how our knowledge of cancer development might lead us to reconsider our clinical approach to early detection and prevention of cancer at an individual and population level.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aToxicology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aPharmacology/Toxicology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441966933
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6694-0
912 _aZDB-2-SBL
999 _c105629
_d105629