000 02558nam a22004575i 4500
001 978-94-007-4819-4
003 DE-He213
005 20140220083347.0
007 cr nn 008mamaa
008 120930s2012 ne | s |||| 0|eng d
020 _a9789400748194
_9978-94-007-4819-4
024 7 _a10.1007/978-94-007-4819-4
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aAzmi, Asfar S.
_eeditor.
245 1 0 _aSystems Biology in Cancer Research and Drug Discovery
_h[electronic resource] /
_cedited by Asfar S. Azmi.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2012.
300 _aXII, 423 p. 80 illus., 59 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
520 _aSystems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aBioinformatics.
650 0 _aBiological models.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aCancer Research.
650 2 4 _aSystems Biology.
650 2 4 _aBioinformatics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400748187
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-4819-4
912 _aZDB-2-SBL
999 _c104818
_d104818