000 03890nam a22005295i 4500
001 978-94-007-2004-6
003 DE-He213
005 20140220083339.0
007 cr nn 008mamaa
008 110905s2012 ne | s |||| 0|eng d
020 _a9789400720046
_9978-94-007-2004-6
024 7 _a10.1007/978-94-007-2004-6
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aKamkin, Andre.
_eeditor.
245 1 0 _aMechanical Stretch and Cytokines
_h[electronic resource] /
_cedited by Andre Kamkin, Irina Kiseleva.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2012.
300 _aXVI, 236 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMechanosensitivity in Cells and Tissues ;
_v5
505 0 _aForeword by Leonid V. Rosenshtraukh; Editorial, Andre Kamkin and Irina Kiseleva -- 1 Cytokine System, Andrey A. Simbirtsev and Ivan G. Kozlov -- 2 Mechanical stretching of cells of different tissues: The role of mediators of innate immunity, Leonid V. Kovalchuk et al -- 3 Mechanosensitive pro-inflammatory gene expression in vascular cells, Marco Cattaruzza, Andreas H. Wagner, and Markus Hecker -- 4 Cytokines, heart and calcium current in sepsis, Stengl Milan, Prucha Miroslav, and Matejovic Martin -- 5 The role of proinflammatory cytokines in regulation of cardiac bioelectrical activity: Link to mechanoelectrical feedback, Vlad S. Kuzmin et al -- 6 An Anti-inflammatory Cytokine Interleukin-13: Physiological Role in the Heart and Mechanoelectrical Feedback, Denis V. Abramochkin et al -- 7 Mechanical Stretch and Cytokine Synthesis in Pulmonary Endothelial Cells, Satoru Ito and Yoshinori Hasegawa -- 8 Implications of cytokines in cochlear pathophysiology, Keiji Tabuchi and Akira Hara -- 9 Primary cilia are mechanosensory organelles with chemosensory roles, Brian S. Muntean, Xingjian Jin, and Surya M. Nauli -- 10 Identification of mechanosensitive genes in chondrocytes and osteoblasts and their role in OA pathogenesis, Yves Henrotin, Laurence Pesesse, and Christelle Sanchez -- Index.
520 _aThis book presents the latest findings in the field of investigation of molecular mechanisms of mechanical stretch and the role of cytokines in response of different tissues to it. On the one hand this Volume demonstrates how mechanical stretch enhances cytokines production. It describes how cytokines influence tissues and cells on a background of a mechanical stretching. It provides a description of how cells in different tissues are activated by stretch and cytokines via various signaling pathways, and how they change their gene expression. The book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Knowledge of biomechanics, and mechanisms which underlie it on molecular, cellular and tissue, is necessary for understanding of the normal functioning of living organisms and allows to predict changes, which arise due to alterations of their environment.
650 0 _aLife sciences.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aImmunology.
650 0 _aCytology.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aBiomedicine general.
650 2 4 _aHuman Physiology.
650 2 4 _aImmunology.
650 2 4 _aMolecular Medicine.
700 1 _aKiseleva, Irina.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400720039
830 0 _aMechanosensitivity in Cells and Tissues ;
_v5
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-2004-6
912 _aZDB-2-SBL
999 _c104361
_d104361