000 03259nam a22005055i 4500
001 978-88-470-1705-4
003 DE-He213
005 20140220083334.0
007 cr nn 008mamaa
008 111118s2012 it | s |||| 0|eng d
020 _a9788847017054
_9978-88-470-1705-4
024 7 _a10.1007/978-88-470-1705-4
_2doi
050 4 _aRC841-858.P35
072 7 _aMJJ
_2bicssc
072 7 _aMED031000
_2bisacsh
082 0 4 _a616.36
_223
100 1 _aDammacco, Franco.
_eeditor.
245 1 0 _aHCV Infection and Cryoglobulinemia
_h[electronic resource] /
_cedited by Franco Dammacco.
264 1 _aMilano :
_bSpringer Milan :
_bImprint: Springer,
_c2012.
300 _aXVII, 360p. 64 illus., 52 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aHepatitis C virus infection and the role of the immune system -- Cryoglobulinemia: immunochemical characterization, serological abnormalities and histopathological changes -- Structural and genetic features, cytokines and chemokines in cryoglobulinemia -- Cellular compartments of HCV infection (and replication) - Mechanism(s) of cryoprecipitation -- Clinical manifestations of cryoglobulinemia -- HCV infection, cryoglobulinemia and non-Hodgkin’s lymphomas -- Therapy of cryoglobulinemia.
520 _aIn 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These “cryoglobulins” were responsible for the corresponding clinical condition “cryoglobulinemia.” Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia. Subsequent progress in this field was rather slow until the end of the 1980s, when cryoglobulinemia was definitively shown to be an extrahepatic manifestation of hepatitis C virus infection. The book is unique in its detailed presentation and fundamental approach. Highly qualified authors have contributed critical articles reviewing significant developments in our understanding of and therapeutic approach to HCV infection and cryoglobulinemia. The text is accompanied by striking color images and illustrations and highly informative tables. This comprehensive review of a systemic disease with a complex etiology is a valuable source of up-to-date, expert information not only for basic scientists and specialists in several disciplines but also for general practitioners as well as graduate and post-graduate students in clinical and medical research.
650 0 _aMedicine.
650 0 _aInternal medicine.
650 0 _aClinical medicine.
650 0 _aEmerging infectious diseases.
650 0 _aOncology.
650 0 _aRheumatology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aHepatology.
650 2 4 _aInternal Medicine.
650 2 4 _aInfectious Diseases.
650 2 4 _aRheumatology.
650 2 4 _aOncology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9788847017047
856 4 0 _uhttp://dx.doi.org/10.1007/978-88-470-1705-4
912 _aZDB-2-SME
999 _c104078
_d104078