| 000 | 02435nam a22004695i 4500 | ||
|---|---|---|---|
| 001 | 978-4-431-54043-4 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083333.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 111122s2012 ja | s |||| 0|eng d | ||
| 020 |
_a9784431540434 _9978-4-431-54043-4 |
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| 024 | 7 |
_a10.1007/978-4-431-54043-4 _2doi |
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| 050 | 4 | _aQD241-441 | |
| 072 | 7 |
_aPSB _2bicssc |
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| 072 | 7 |
_aSCI013040 _2bisacsh |
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| 072 | 7 |
_aSCI007000 _2bisacsh |
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| 082 | 0 | 4 |
_a547 _223 |
| 100 | 1 |
_aInuki, Shinsuke. _eauthor. |
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| 245 | 1 | 0 |
_aTotal Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds _h[electronic resource] / _cby Shinsuke Inuki. |
| 264 | 1 |
_aTokyo : _bSpringer Tokyo, _c2012. |
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| 300 |
_aXVI, 106 p. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 | _aSpringer Theses | |
| 505 | 0 | _aChapter 1. Total Synthesis of Pachastrissamine (Jaspine B) -- Chapter 2. Total Synthesis of Lysergic Acid, Lysergol, and Isolysergol -- Chapter 3. Conclusions. | |
| 520 | _aThe author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure. | ||
| 650 | 0 | _aChemistry. | |
| 650 | 0 | _aBioorganic chemistry. | |
| 650 | 0 | _aCatalysis. | |
| 650 | 1 | 4 | _aChemistry. |
| 650 | 2 | 4 | _aBioorganic Chemistry. |
| 650 | 2 | 4 | _aCatalysis. |
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9784431540427 |
| 830 | 0 | _aSpringer Theses | |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-4-431-54043-4 |
| 912 | _aZDB-2-CMS | ||
| 999 |
_c104035 _d104035 |
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