000			03886nam a22005055i 4500
001			978-3-7091-0709-6
003			DE-He213
005			20140220083332.0
007			cr nn 008mamaa
008			120420s2012 au | s |||| 0|eng d
020			_a9783709107096 _9978-3-7091-0709-6
024	7		_a10.1007/978-3-7091-0709-6 _2doi
050		4	_aRM281
050		4	_aQR189-189.5
072		7	_aMJCM _2bicssc
072		7	_aMED044000 _2bisacsh
082	0	4	_a615.372 _223
100	1		_avon Gabain, Alexander. _eeditor.
245	1	0	_aDevelopment of Novel Vaccines _h[electronic resource] : _bSkills, Knowledge and Translational Technologies / _cedited by Alexander von Gabain, Christoph Klade.
264		1	_aVienna : _bSpringer Vienna, _c2012.
300			_aXIII, 303p. 52 illus., 30 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPreface -- 1. The immunological fundamentals (Şefik Şanal Alkan) -- 2. Finding protective bacterial antigens (Guido Grandi, Eszter Nagy) -- 3. Enhancing and tailoring the immunogenicity of vaccines with novel adjuvants (Christopher B. Fox, Benjamin Wizel, Steven G. Reed, Derek T. O’Hagan) -- 4. Vaccine Delivery – beyond needles (Flyer) -- 5. Employing live microbes for vaccine delivery (Holger Loessner, Astrid Schwantes, Matthias Hamdorf, Uliana Komor, Sara Leschner, Siegfried Weiss) -- 6. Synthesizing vaccines with microbes (Michael Wacker, Danilo R. Casimiro) -- 7. Purification and formulation: silent but important players in vaccine development (Robert Schlegl, Rainer Hahn) -- 8. Cutting edge approaches towards novel and cross protective influenza vaccines (Ruth Arnon, Tamar Ben-Yedidia) -- 9. Cutting edge approaches towards novel and cross-protective influenza vaccines (Kenny Roose, Michael Schotsaert, Karim El Bakkouri, Bert Schepens, Walter Fiers, Xavier Saelens) -- 10. Examples of novel registered prophylactic vaccines, HPV & JEV (Katrin Dubischar-Kastner, Michelle Vichnin, Carlos Sattler) -- 11. The bumpy road towards vaccine registration – how to overcome regulatory hurdles (Michael Pfleiderer).
520			_a“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions.  Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.
650		0	_aMedicine.
650		0	_aImmunology.
650		0	_aMedical laboratories.
650		0	_aVaccines.
650		0	_aPharmaceutical technology.
650	1	4	_aBiomedicine.
650	2	4	_aVaccine.
650	2	4	_aPharmaceutical Sciences/Technology.
650	2	4	_aImmunology.
650	2	4	_aLaboratory Medicine.
700	1		_aKlade, Christoph. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783709107089
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-7091-0709-6
912			_aZDB-2-SBL
999			_c103909 _d103909