000 03239nam a22004935i 4500
001 978-3-7091-0338-8
003 DE-He213
005 20140220083332.0
007 cr nn 008mamaa
008 111202s2012 au | s |||| 0|eng d
020 _a9783709103388
_9978-3-7091-0338-8
024 7 _a10.1007/978-3-7091-0338-8
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
100 1 _aWick, Georg.
_eeditor.
245 1 0 _aInflammation and Atherosclerosis
_h[electronic resource] /
_cedited by Georg Wick, Cecilia Grundtman.
264 1 _aVienna :
_bSpringer Vienna,
_c2012.
300 _aIX, 631 p. 84 illus., 53 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1 Historical Reflections on the Inflammatory Aspects of Atherosclerosis -- 2 Morphology and Clinical Manifestations -- 3 The Vascular System as an Immunological Tissue and an Immunopathological Target.- 4 Animal Models of Atherosclerosis.- 5 A Darwinian-Evolutionary Concept for Atherogenesis: The Role of Immunity to HSP 60.- 6 Mediators of Inflammation and Their Target Cells.- 7 Innate Immunity.- 8 Adaptive Immunity.- 9 Immunity to Low-Density Lipoprotein.- 10 Extracellular Matrix and Smooth Muscle Cells.- 11 The Role of Infection in Atherosclerosis and in Plaque Stability.- 12 Inflammatory Biomarkers.- 13 Atherosclerosis in Rheumatic Diseases.- 14 Anti-Inflammatory Therapeutic Approaches.- 15 Vaccination Against Atherosclerosis.- 16 Endocrinological Aspects of Atherosclerosis.- 17 Imaging of Atherosclerosis.- 18 Future Directions of Atherosclerosis Research and Translation into Clinical Application.- 19 Controversies and Open Questions.
520 _aIt has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aImmunology.
650 0 _aVaccines.
650 0 _aEndocrinology.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aHuman Physiology.
650 2 4 _aEndocrinology.
650 2 4 _aVaccine.
700 1 _aGrundtman, Cecilia.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783709103371
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-7091-0338-8
912 _aZDB-2-SBL
999 _c103902
_d103902