000 04018nam a22004815i 4500
001 978-3-642-30991-5
003 DE-He213
005 20140220083320.0
007 cr nn 008mamaa
008 120913s2012 gw | s |||| 0|eng d
020 _a9783642309915
_9978-3-642-30991-5
024 7 _a10.1007/978-3-642-30991-5
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
100 1 _aDenys, Damiaan.
_eeditor.
245 1 0 _aDeep Brain Stimulation
_h[electronic resource] :
_bA New Frontier in Psychiatry /
_cedited by Damiaan Denys, Matthijs Feenstra, Rick Schuurman.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2012.
300 _aXI, 299 p. 38 illus., 26 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aBasic principles of deep brain stimulation -- Neural circuits affected by DBS for psychiatric disorders -- Mechanisms of action of SBS for psychiatric disorders -- DBS for obsessive-compulsive disorder -- Obsessive-compulsive disorders in animals -- Subcallosal cingulate cortex DBS for treatment resistant mood disorders -- DBS to the human reward system as a putative treatment for refractory major depression -- DBS in animal models of depression -- DBS in Tourette syndrome -- Surgical treatments for drug addictions in humans -- Manipulating addictive behaviour in animal models -- Neuropsychiatric side effects of DBS in Parkinson's disease -- Psychiatric aspects of Parkinson's disease in animal models -- Scientific recordings in DBS -- Neurotransmitter release during DBS -- The potential role of non-neuronal cells in the DBS mechanism -- What are glia? Could they be players in DBS -- Animal studies in DBS research -- Neuroimaging of DBS in psychiatric disorders -- Optogenetic strategies for neuropsychiatric disorders: Circuit-function analysis and clinical implications -- Next generation electrodes for steering brain stimulation -- Future applications: nanotechniques -- Ethical guidance for the use of DBS in psychiatric trials and emerging uses: Review and reflections.
520 _aDeep Brain Stimulation: A New Frontier in Psychiatry provides an overview of current developments and the future possibilities of deep brain stimulation for patients with therapy-refractory psychiatric disorders. The side-by-side presentation of clinical applications and animal research provides a truly translational approach. Also included is a special chapter on the ethical issues involved in deep brain stimulation in psychiatry. Deep brain stimulation of selected brain areas has been shown to result in a substantial improvement of symptoms and quality of life in patients suffering from obsessive-compulsive disorder, major depressive disorder and drug addiction. Although it is still an experimental therapy and the number of psychiatric patients that are treated is low, its effectiveness and safety makes deep brain stimulation the most promising therapy for treating other serious and life-threatening psychiatric conditions. Deep Brain Stimulation: A New Frontier in Psychiatry is written for researchers in the area of (bio)medicine, life sciences, psychiatry, psychology, functional neurosurgery, neurosciences and neurobiology.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aPsychiatry.
650 0 _aNeurobiology.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aPsychiatry.
650 2 4 _aNeurobiology.
700 1 _aFeenstra, Matthijs.
_eeditor.
700 1 _aSchuurman, Rick.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642309908
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-30991-5
912 _aZDB-2-SBL
999 _c103283
_d103283