000 03562nam a22004815i 4500
001 978-3-642-29819-6
003 DE-He213
005 20140220083317.0
007 cr nn 008mamaa
008 120905s2012 gw | s |||| 0|eng d
020 _a9783642298196
_9978-3-642-29819-6
024 7 _a10.1007/978-3-642-29819-6
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
100 1 _aLee, Benhur.
_eeditor.
245 1 0 _aHenipavirus
_h[electronic resource] :
_bEcology, Molecular Virology, and Pathogenesis /
_cedited by Benhur Lee, Paul A. Rota.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2012.
300 _aXI, 226 p. 26 illus., 19 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v359
520 _aHenipaviruses form a new genus of emerging paramyxoviruses that are the deadliest human pathogens within the Paramyxoviridae family. This volume deals with the many facets of henipavirus biology, and covers our current understanding regarding the ecology, molecular virology, and pathogenesis of henipavirus infections. It is an international effort written by a multidisciplinary panel of experts at the front lines of research into this lethal emerging group of paramyxoviruses. The first section introduces the epidemiology and ecology of Nipah and Hendra viruses in their respective endemic areas, including a first-hand account of the discovery of Nipah virus during its initial outbreak in Malaysia; the next section documents the molecular virology of henipaviruses, and the substantial advances made towards understanding the unique features of henipavirus entry and tropism; and this is followed by accounts of the clinical and pathologic features of henipavirus infections in their human and naturally infected animal hosts. The next sections on pathogenesis provide a comprehensive reference on how henipaviruses counteract the innate immune system, and the relevant pathogenic features in animal challenge models developed to test potential therapeutic strategies. The final sections describe our current and future capabilities for diagnosis and control, including an account of potentially effective immunization strategies that are currently being tested.    This book will not only serve as a useful reference for the henipavirus field; it will be useful to basic and animal virologists, ecologists, epidemiologists, physicians, and others interested in emerging infectious viral diseases, as it showcases the multidisciplinary efforts required to understand the genesis, spread and hopefully, control, of a group of lethal emerging zoonotic pathogens.  
650 0 _aMedicine.
650 0 _aVaccines.
650 0 _aMedical virology.
650 0 _aWildlife management.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
650 2 4 _aVaccine.
650 2 4 _aFish & Wildlife Biology & Management.
700 1 _aRota, Paul A.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642298189
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v359
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-29819-6
912 _aZDB-2-SBL
999 _c103088
_d103088