000 03025nam a22005535i 4500
001 978-3-642-29423-5
003 DE-He213
005 20140220083316.0
007 cr nn 008mamaa
008 120823s2012 gw | s |||| 0|eng d
020 _a9783642294235
_9978-3-642-29423-5
024 7 _a10.1007/978-3-642-29423-5
_2doi
050 4 _aRM1-950
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
082 0 4 _a615
_223
100 1 _aGresele, Paolo.
_eeditor.
245 1 0 _aAntiplatelet Agents
_h[electronic resource] /
_cedited by Paolo Gresele, Gustav V. R Born, Carlo Patrono, Clive P. Page.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2012.
300 _aXII, 616 p. 62 illus., 47 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v210
505 0 _aForeword -- Preface -- Part 1.  Pathophysiology -- Part 2. Pharmacology -- Part 3. Therapy.
520 _aAntiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.
650 0 _aMedicine.
650 0 _aToxicology.
650 0 _aInternal medicine.
650 0 _aCardiology.
650 0 _aNeurology.
650 1 4 _aBiomedicine.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aCardiology.
650 2 4 _aInternal Medicine.
650 2 4 _aNeurology.
650 2 4 _aMolecular Medicine.
700 1 _aBorn, Gustav V. R.
_eeditor.
700 1 _aPatrono, Carlo.
_eeditor.
700 1 _aPage, Clive P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642294228
830 0 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v210
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-29423-5
912 _aZDB-2-SBL
999 _c103030
_d103030