000			03427nam a22004935i 4500
001			978-3-642-27540-1
003			DE-He213
005			20140220083308.0
007			cr nn 008mamaa
008			120120s2012 gw | s |||| 0|eng d
020			_a9783642275401 _9978-3-642-27540-1
024	7		_a10.1007/978-3-642-27540-1 _2doi
050		4	_aQD415-436
072		7	_aPNN _2bicssc
072		7	_aSCI013040 _2bisacsh
082	0	4	_a547 _223
100	1		_aDavies, Thomas G. _eeditor.
245	1	0	_aFragment-Based Drug Discovery and X-Ray Crystallography _h[electronic resource] / _cedited by Thomas G. Davies, Marko Hyvönen.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2012.
300			_aXI, 225 p. 57 illus., 31 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aTopics in Current Chemistry, _x0340-1022 ; _v317
505	0		_aD. A. Erlanson Introduction to Fragment-Based Drug Discovery -- T. G. Davies Ian J. Tickle Fragment Screening Using X-Ray Crystallography -- S. Roughley L. Wright P. Brough A. Massey R. E. Hubbard Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening -- D. F. Wyss Y.-S. Wang H. L. Eaton C. Strickland J.s H. Voigt Z. Zhu A. W. Stamford Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors -- M. Hennig A. Ruf Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery -- E. Valkov T. Sharpe M. Marsh Sa. Greive M. Hyvönen Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery -- J.h D. Bauman D. Patel E. Arnold Fragment Screening and HIV Therapeutics -- D. Rognan Fragment-Based Approaches and Computer-Aided Drug Discovery.
520			_aD. A. Erlanson Introduction to Fragment-Based Drug Discovery T. G. Davies Ian J. Tickle Fragment Screening Using X-Ray Crystallography S. Roughley L. Wright P. Brough A. Massey R. E. Hubbard Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening D. F. Wyss Y.-S. Wang H. L. Eaton C. Strickland J.s H. Voigt Z. Zhu A. W. Stamford Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors M. Hennig A. Ruf Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery E. Valkov T. Sharpe M. Marsh Sa. Greive M. Hyvönen Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery J.h D. Bauman D. Patel E. Arnold Fragment Screening and HIV Therapeutics D. Rognan Fragment-Based Approaches and Computer-Aided Drug Discovery
650		0	_aChemistry.
650		0	_aPharmaceutical technology.
650		0	_aChemistry, Organic.
650		0	_aCrystallography.
650	1	4	_aChemistry.
650	2	4	_aOrganic Chemistry.
650	2	4	_aCrystallography.
650	2	4	_aPharmaceutical Sciences/Technology.
700	1		_aHyvönen, Marko. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642275395
830		0	_aTopics in Current Chemistry, _x0340-1022 ; _v317
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-27540-1
912			_aZDB-2-CMS
999			_c102615 _d102615