| 000 | 03286nam a22005055i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-27426-8 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083308.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 120612s2012 gw | s |||| 0|eng d | ||
| 020 |
_a9783642274268 _9978-3-642-27426-8 |
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| 024 | 7 |
_a10.1007/978-3-642-27426-8 _2doi |
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| 050 | 4 | _aQH506 | |
| 072 | 7 |
_aMBGR _2bicssc |
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| 072 | 7 |
_aPSD _2bicssc |
|
| 072 | 7 |
_aSCI049000 _2bisacsh |
|
| 072 | 7 |
_aMED067000 _2bisacsh |
|
| 082 | 0 | 4 |
_a611.01816 _223 |
| 100 | 1 |
_aErdmann, Volker A. _eeditor. |
|
| 245 | 1 | 0 |
_aFrom Nucleic Acids Sequences to Molecular Medicine _h[electronic resource] / _cedited by Volker A. Erdmann, Jan Barciszewski. |
| 264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2012. |
|
| 300 |
_aIX, 654 p. 120 illus., 42 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 | _aRNA Technologies | |
| 505 | 0 | _aFrom the contents -- Preface -- RNA (center of the) World. Non-coding RNAs: Identification of Cancer-Associated microRNAs. Antisense Oligonucleotides in the Treatment of Malignant Gliomas. The diverse active sites in splicing, debranching and microRNA processing around RNA phosphodiester bonds. Activation and Deactivation of Antisense Function with Light. Targeting catalytic RNAs into mitochondria for functional analyses and inverse genetics. Ribozymes as molecular biology reagents. Natural antisense transcripts mediate regulation of gene expression. Hammerhead ribozymes against virus and viroid RNAs. Chemical modification of short shRNAs. Antisense for treatment of cancer: the present and the future. Targeting non-coding RNAs for cancer therapy. Suppression of hepatitis C viral genome replication with Functional Antisense Oligonucleotides. Antisense-mediated reduction of eukaryotic non-coding RNAs. | |
| 520 | _aFor this RNA Technologies volume a world-wide outstanding group of RNA specialists are contributing the most recent developments in this fast moving field of RNA molecular biology. The book features up-to-date information of our current knowledge on antisense, ribozyme, micro RNA, and DNAzyme strategies, as well as on other small RNAs from eukaryotes and prokaryotes, and the employment of chemical modifications to stabilize ribonucleic acids for their use in living cells. This volume is not only excellent reading for the expert in the field of RNA technologies, but also for those interested in entering this field as a chemist, molecular biologist or as a medical doctor interested in RNA therapeutics of the future. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aHuman genetics. | |
| 650 | 0 | _aNucleic acids. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aMolecular Medicine. |
| 650 | 2 | 4 | _aNucleic Acid Chemistry. |
| 650 | 2 | 4 | _aHuman Genetics. |
| 700 | 1 |
_aBarciszewski, Jan. _eeditor. |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783642274251 |
| 830 | 0 | _aRNA Technologies | |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-642-27426-8 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c102587 _d102587 |
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