000			03034nam a22005415i 4500
001			978-3-642-23056-1
003			DE-He213
005			20140220083300.0
007			cr nn 008mamaa
008			120507s2012 gw | s |||| 0|eng d
020			_a9783642230561 _9978-3-642-23056-1
024	7		_a10.1007/978-3-642-23056-1 _2doi
050		4	_aRM1-950
072		7	_aMMG _2bicssc
072		7	_aMED071000 _2bisacsh
082	0	4	_a615 _223
100	1		_aLever, Rebecca. _eeditor.
245	1	0	_aHeparin - A Century of Progress _h[electronic resource] / _cedited by Rebecca Lever, Barbara Mulloy, Clive P. Page.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2012.
300			_aXIV, 459p. 79 illus., 4 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aHandbook of Experimental Pharmacology, _x0171-2004 ; _v207
505	0		_aPart 1. Introduction -- Part 2. Unfractionated and Low Molecular Weight Heparins -- Part 3. Clinical Use of Heparin and LMWH -- Part 4. Non Anticoagulant Indictions for Heparin and Related Compounds -- Part 5. Heparin-like Entities.
520			_aHeparins remain amongst the most commonly used drugs in clinical practice.  Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.
650		0	_aMedicine.
650		0	_aToxicology.
650		0	_aPharmaceutical technology.
650		0	_aInternal medicine.
650		0	_aHematology.
650	1	4	_aBiomedicine.
650	2	4	_aPharmacology/Toxicology.
650	2	4	_aMolecular Medicine.
650	2	4	_aPharmaceutical Sciences/Technology.
650	2	4	_aInternal Medicine.
650	2	4	_aHematology.
700	1		_aMulloy, Barbara. _eeditor.
700	1		_aPage, Clive P. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642230554
830		0	_aHandbook of Experimental Pharmacology, _x0171-2004 ; _v207
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-23056-1
912			_aZDB-2-SBL
999			_c102121 _d102121