| 000 | 02428nam a22004575i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-21892-7 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083258.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 120203s2012 gw | s |||| 0|eng d | ||
| 020 |
_a9783642218927 _9978-3-642-21892-7 |
||
| 024 | 7 |
_a10.1007/978-3-642-21892-7 _2doi |
|
| 050 | 4 | _aRC254-282 | |
| 072 | 7 |
_aMJCL _2bicssc |
|
| 072 | 7 |
_aMED062000 _2bisacsh |
|
| 082 | 0 | 4 |
_a616.994 _223 |
| 100 | 1 |
_aJoerger, Markus. _eeditor. |
|
| 245 | 1 | 0 |
_aPrevention of Bone Metastases _h[electronic resource] / _cedited by Markus Joerger, Michael Gnant. |
| 264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2012. |
|
| 300 |
_aIX, 233p. 23 illus., 13 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aRecent Results in Cancer Research, _x0080-0015 ; _v192 |
|
| 520 | _aBone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aOncology. | |
| 650 | 0 |
_aCancer _xSurgery. |
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| 650 | 1 | 4 | _aMedicine & Public Health. |
| 650 | 2 | 4 | _aOncology. |
| 650 | 2 | 4 | _aSurgical Oncology. |
| 700 | 1 |
_aGnant, Michael. _eeditor. |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783642218910 |
| 830 | 0 |
_aRecent Results in Cancer Research, _x0080-0015 ; _v192 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-642-21892-7 |
| 912 | _aZDB-2-SME | ||
| 999 |
_c102007 _d102007 |
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