000 02787nam a22004695i 4500
001 978-3-0348-0445-5
003 DE-He213
005 20140220083254.0
007 cr nn 008mamaa
008 120703s2012 sz | s |||| 0|eng d
020 _a9783034804455
_9978-3-0348-0445-5
024 7 _a10.1007/978-3-0348-0445-5
_2doi
050 4 _aQH506
072 7 _aMBGR
_2bicssc
072 7 _aPSD
_2bicssc
072 7 _aSCI049000
_2bisacsh
072 7 _aMED067000
_2bisacsh
082 0 4 _a611.01816
_223
100 1 _aStein-Streilein, Joan.
_eeditor.
245 1 0 _aInfection, Immune Homeostasis and Immune Privilege
_h[electronic resource] /
_cedited by Joan Stein-Streilein.
264 1 _aBasel :
_bSpringer Basel :
_bImprint: Springer,
_c2012.
300 _aXI, 153 p. 12 illus., 7 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBirkhäuser Advances in Infectious Diseases
505 0 _aIntroduction -- The Eye as Immune Privileged Site -- Immune Privilege of the Testis – Meaning, Mechanisms and Manifestations -- The Role of Intrauterine Immune Privilege in Perinatal Infectious Diseases -- The Liver as an Immune Privileged Site -- Immune Homeostasis of the Lung: The Role of Regulatory NKT Cells in Asthma -- Immune Homeostasis of the Gut.
520 _aOrgans and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.
650 0 _aMedicine.
650 0 _aMicrobiology.
650 1 4 _aBiomedicine.
650 2 4 _aMolecular Medicine.
650 2 4 _aMedical Microbiology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783034804448
830 0 _aBirkhäuser Advances in Infectious Diseases
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-0348-0445-5
912 _aZDB-2-SBL
999 _c101750
_d101750