000 05296nam a22005055i 4500
001 978-1-84882-448-5
003 DE-He213
005 20140220083252.0
007 cr nn 008mamaa
008 120210s2012 xxk| s |||| 0|eng d
020 _a9781848824485
_9978-1-84882-448-5
024 7 _a10.1007/978-1-84882-448-5
_2doi
050 4 _aR858-859.7
072 7 _aMBG
_2bicssc
072 7 _aUB
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a502.85
_223
100 1 _aRichesson, Rachel L.
_eeditor.
245 1 0 _aClinical Research Informatics
_h[electronic resource] /
_cedited by Rachel L. Richesson, James E. Andrews.
264 1 _aLondon :
_bSpringer London,
_c2012.
300 _aX, 422 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aHealth Informatics,
_x1431-1917
505 0 _aSection I: Contexts of Clinical Research Informatics -- Introduction to Clinical Research Informatics -- From Notations to Data: The Digital Transformation of Clinical Research -- Clinical Research Environment. - Statistical and Study Design Foundations of Clinical Research -- Informatics Approaches to Participant Recruitment -- The Evolving Role of Consumers -- Clinical Research in the Post-Genomic Era -- Section II: Data Management and Systems in Clinical Research -- Clinical Research Information Systems -- Study Protocol Representation -- Data Quality in Clinical Research -- Patient-Reported Outcome Data.- Biobanking Challenges and Informatics Opportunities -- Patient Registries -- Section III: Knowledge Representation and Discovery -- Knowledge Representation and Ontologies -- Non-hypothesis Driven Research: Data Mining and Knowledge Discovery -- Natural Language Processing, Electronic Health Records, and Clinical Research -- Section IV: The Future of Clinical Research, Health, and Clinical Research Informatics -- Data Sharing: Electronic Health Records and Research Interoperability -- Standards Development and the Future of Research Data Sources, Interoperability, and Exchange -- Pharmacovigilance -- Clinical Trials Registries and Results Databases -- Future Directions in Clinical Research Informatics -- Index.
520 _aClinical research informatics (CRI) is the application of informatics principles and techniques to support the spectrum of activities and business processes that instantiate clinical research. Informatics, defined generally as the intersection of information and computer science with a health-related discipline, has a foundation drawn from many well-established, theory-based disciplines, including computer science, library and information science, cognitive science, psychology, and sociology. The newly articulated yet fundamental theorem of informatics states that information technology should be used to enable humans to function and perform better together than humans alone, and so informatics is a source for supportive technologies and tools that enhance – but not replace – unreservedly human processes. Clinical Research Informatics contributes to the ongoing dialogues among researchers and practitioners in CRI as they continue to rise to the challenges of a dynamic and evolving clinical research environment. The development of CRI as a sub-discipline of informatics, and as an independent/maturing professional practice area in its own right, drives a growing pool of scientific literature based on original CRI research, and high-impact tools and systems will be developed. CRI leaders and stakeholder groups will continue to support and create communities of discourse that will address much needed practice standards in CRI, improved safety and efficiencies in clinical research, data standards in clinical research, policy issues, educational standards and instructional resources. The Editors and contributors to this book are among the most active and engaged in the CRI domain and provide an excellent primer for deeper explorations into this emerging discipline. Certain themes are highlighted, including the changing role of the consumer, movement toward transparency, growing needs for global coordination and cooperation on many levels, and the merging together of clinical care delivery and research as part of a changing paradigm in global healthcare delivery – all in the context of rapid innovations in technology and explosions of data sources, types, and volume. This book is therefore of considerable interest to all students of biomedical informatics, from the newcomer to the professional informatician.
650 0 _aMedicine.
650 0 _aMedical laboratories.
650 0 _aPractice of medicine.
650 0 _aMedical records
_xData processing.
650 1 4 _aMedicine & Public Health.
650 2 4 _aHealth Informatics.
650 2 4 _aHealth Administration.
650 2 4 _aLaboratory Medicine.
700 1 _aAndrews, James E.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781848824478
830 0 _aHealth Informatics,
_x1431-1917
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-84882-448-5
912 _aZDB-2-SME
999 _c101645
_d101645