000			03847nam a22004815i 4500
001			978-1-61779-891-7
003			DE-He213
005			20140220083252.0
007			cr nn 008mamaa
008			120703s2012 xxu| s |||| 0|eng d
020			_a9781617798917 _9978-1-61779-891-7
024	7		_a10.1007/978-1-61779-891-7 _2doi
050		4	_aRB1-214
072		7	_aMMF _2bicssc
072		7	_aMED067000 _2bisacsh
082	0	4	_a616.07 _223
100	1		_aPatterson, Cam. _eeditor.
245	1	0	_aTranslational Cardiology _h[electronic resource] : _bMolecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques / _cedited by Cam Patterson, Monte S. Willis.
264		1	_aTotowa, NJ : _bHumana Press : _bImprint: Humana Press, _c2012.
300			_aXV, 543 p. 67 illus., 52 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aMolecular and Translational Medicine
505	0		_aRelationship Between Myocardial Ischemia/Reperfusion and Time-of-Day -- Phosphotransfer Reactions in the Failing Heart -- Mitochondria in Cardiac Disease -- PPAR/PGC-1 Regulation of Metabolism in Cardiac Disease -- AMPK and Metabolic Remodeling in Cardiac Disease -- Mechanotransduction in Cardiac Hypertrophy and Ischemia -- Cardiac Plasticity in Health and Disease -- Ubiquitylation‐Dependent Signaling in Heart Disease -- Mechanisms of Cardiac Dysfunction Associated with Cancer Therapeutics -- Molecular Basis of Cardiac Development and Congenital Heart Disease -- Cellular Therapy for the Infarcted Myocardium -- Novel Approaches to Deliver Molecular Therapeutics in Cardiac Disease Using Adeno-Associated Virus Vectors -- Novel Delivery of Molecular Therapeutics to the Heart Using Non-Biologic Constructs (PPMO/Morpholino) in Muscular Dystrophy -- Molecular Imaging of Cardiovascular Disease.
520			_aTranslational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.
650		0	_aMedicine.
650		0	_aCardiology.
650		0	_aPathology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aPathology.
650	2	4	_aCardiology.
650	2	4	_aMolecular Medicine.
700	1		_aWillis, Monte S. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781617798900
830		0	_aMolecular and Translational Medicine
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-61779-891-7
912			_aZDB-2-SME
999			_c101624 _d101624