000 03415nam a22004335i 4500
001 978-1-61779-394-3
003 DE-He213
005 20140220083251.0
007 cr nn 008mamaa
008 111214s2012 xxu| s |||| 0|eng d
020 _a9781617793943
_9978-1-61779-394-3
024 7 _a10.1007/978-1-61779-394-3
_2doi
050 4 _aRB1-214
072 7 _aMMF
_2bicssc
072 7 _aMED067000
_2bisacsh
082 0 4 _a616.07
_223
100 1 _aHui, Pei.
_eeditor.
245 1 0 _aGestational Trophoblastic Disease
_h[electronic resource] :
_bDiagnostic and Molecular Genetic Pathology /
_cedited by Pei Hui.
264 1 _aNew York, NY :
_bSpringer New York,
_c2012.
300 _aXIII, 205p. 104 illus., 96 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Clinical Pathology
505 0 _aForward -- Preface and Dedication.- Gestational Trophoblastic Disease: General Aspects -- Developmental Biology of the Placenta -- Genetic Basis of Gestational Trophoblastic Disease -- Complete hydatidiform mole.- Partial hydatidiform mole -- Placental site trophoblastic tumor (PSTT) -- Epithelioid trophoblastic tumor.-Gestational choriocarcinoma -- Persistent gestational trophoblastic neoplasia -- Tumor-like trophoblastic conditions -- Molecular Diagnosis of Gestational Trophoblastic Disease -- Clinical aspects of gestational trophoblastic disease -- Appendix.
520 _aIn this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations. Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.
650 0 _aMedicine.
650 0 _aPathology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aPathology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781617793936
830 0 _aCurrent Clinical Pathology
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-61779-394-3
912 _aZDB-2-SME
999 _c101602
_d101602