000 03907nam a22005415i 4500
001 978-1-61091-221-1
003 DE-He213
005 20140220083251.0
007 cr nn 008mamaa
008 120630s2012 xxu| s |||| 0|eng d
020 _a9781610912211
_9978-1-61091-221-1
024 7 _a10.5822/978-1-61091-221-1
_2doi
050 4 _aGE1-350
072 7 _aRNP
_2bicssc
072 7 _aSCI026000
_2bisacsh
072 7 _aSCI013000
_2bisacsh
082 0 4 _a577.14
_223
100 1 _aMonosson, Emily.
_eauthor.
245 1 0 _aEvolution in a Toxic World
_h[electronic resource] :
_bHow Life Responds to Chemical Threats /
_cby Emily Monosson.
264 1 _aWashington, DC :
_bIsland Press/Center for Resource Economics,
_c2012.
300 _aXIV, 226p. 10 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPreface -- Acknowledgments -- 1. An Introduction -- Part 1: Element. 2. Shining a Light on Earth’s Oldest Toxic Threat? -- 3. When Life Gives You Oxygen, Respire -- 4. Metal Planet -- Part 2: Plant and Animal. 5. It Takes Two (or More) for the Cancer Tango -- 6. Chemical Warfare -- 7. Sensing Chemicals -- 8. Coordinated Defense -- Part 3: Human. 9. Toxic Evolution -- 10. Toxic Overload? -- Appendix: Five Recent Additions to the Chemical Handbook of Life Notes -- Selected Bibliography -- Index.
520 _aWith BPA in baby bottles, mercury in fish, and lead in computer monitors, the world has become a toxic place. But as Emily Monosson demonstrates in her groundbreaking new book, it has always been toxic. When oxygen first developed in Earth's atmosphere, it threatened the very existence of life: now we literally can't live without it. According to Monosson, examining how life adapted to such early threats can teach us a great deal about today's (and tomorrow's) most dangerous contaminants. While the study of evolution has advanced many other sciences, from conservation biology to medicine, the field of toxicology has yet to embrace this critical approach. In Evolution in a Toxic World, Monosson seeks to change that. She traces the development of life's defense systems—the mechanisms that transform, excrete, and stow away potentially harmful chemicals—from more than three billion years ago to today. Beginning with our earliest ancestors' response to ultraviolet radiation, Monosson explores the evolution of chemical defenses such as antioxidants, metal binding proteins, detoxification, and cell death. As we alter the world's chemistry, these defenses often become overwhelmed faster than our bodies can adapt. But studying how our complex internal defense network currently operates, and how it came to be that way, may allow us to predict how it will react to novel and existing chemicals. This understanding could lead to not only better management and preventative measures, but possibly treatment of current diseases. Development of that knowledge starts with this pioneering book.
650 0 _aEnvironmental sciences.
650 0 _aChemistry.
650 0 _aEndangered ecosystems.
650 0 _aWildlife management.
650 0 _aEnvironmental protection.
650 0 _aEnvironmental chemistry.
650 0 _aEnvironmental toxicology.
650 1 4 _aEnvironment.
650 2 4 _aEnvironmental Chemistry.
650 2 4 _aChemistry/Food Science, general.
650 2 4 _aEcotoxicology.
650 2 4 _aEffects of Radiation/Radiation Protection.
650 2 4 _aFish & Wildlife Biology & Management.
650 2 4 _aEcosystems.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781597263412
856 4 0 _uhttp://dx.doi.org/10.5822/978-1-61091-221-1
912 _aZDB-2-EES
999 _c101588
_d101588