000 03179nam a22004695i 4500
001 978-1-4614-3801-4
003 DE-He213
005 20140220083249.0
007 cr nn 008mamaa
008 120605s2012 xxu| s |||| 0|eng d
020 _a9781461438014
_9978-1-4614-3801-4
024 7 _a10.1007/978-1-4614-3801-4
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
100 1 _aRao, Mahendra S.
_eeditor.
245 1 0 _aNeural Development and Stem Cells
_h[electronic resource] /
_cedited by Mahendra S. Rao, Melissa Carpenter, Mohan C. Vemuri.
250 _a3rd ed. 2012.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2012.
300 _aXII, 500 p. 27 illus., 14 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStem Cell Biology and Regenerative Medicine
505 0 _aDefining Neural Stem Cells and Their Role in Normal Development of the Nervous System -- Embryonic Stem Cells and Neurogenesis -- The Cellular and Molecular Properties of Multipotent Neural Stem Cells -- Multipotent Stem Cells in the Embryonic Nervous System -- Neural Crest Formation and Diversification -- Glial Nature of Adult Neural Stem Cells:  Neurogenic Competence in Adult Astrocytes -- Neural Stem Cell Death Regulation in Nervous System Development and Disease -- Stem Cells of the Adult Olfactory Epithelium -- Retinal Stem Cells -- Transdifferentiation in the Nervous System -- Neural and Dopaminergic Differentiation of Human Pluripotent Stem Cells -- Mobilization of Neural stem cells in the Adult Central Nervous System -- Stem Cell Pathways in Brain Tumors.
520 _aFor the third edition of this work Dr. Rao and his fellow editors have worked diligently with the contributors to revise and expand each chapter.  Additional information about our understanding of the differentiation of pluripotent stem cells into the various neural cell types has been included. Particular attention has been focused on the chapters describing retinal epithelium and neuroglial differentiation, as these cells are currently being delivered in early phase clinical trials. Given the recent findings about the importance of cell death in tumorigenesis, the issue of cell death regulation in the nervous system has been further explored.  The issue of transdifferentiation has also been discussed and extensively updated given the recent findings on direct differentiation and reprogramming of cells.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
700 1 _aCarpenter, Melissa.
_eeditor.
700 1 _aVemuri, Mohan C.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461438007
830 0 _aStem Cell Biology and Regenerative Medicine
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-3801-4
912 _aZDB-2-SBL
999 _c101443
_d101443