000 03192nam a22004695i 4500
001 978-1-4614-2367-6
003 DE-He213
005 20140220083246.0
007 cr nn 008mamaa
008 120308s2012 xxu| s |||| 0|eng d
020 _a9781461423676
_9978-1-4614-2367-6
024 7 _a10.1007/978-1-4614-2367-6
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aMarkowitz, Sanford D.
_eeditor.
245 1 0 _aEnergy Balance and Gastrointestinal Cancer
_h[electronic resource] /
_cedited by Sanford D. Markowitz, Nathan A. Berger.
264 1 _aBoston, MA :
_bSpringer US,
_c2012.
300 _aXII, 184 p. 15 illus., 10 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aEnergy Balance and Cancer ;
_v4
505 0 _aPreface -- Obesity and Gastrointestinal Cancers: Epidemiology -- Genetics of Colon Cancer Susceptibility.- Dietary Modulation of Colon Cancer: Effects on Intermediary Metabolism, Mucosal Cell Differentiation and Inflammation -- The ApcMin/+ Mouse Model to Study the Effects of Exercise on Gastrointestinal Malignancy -- Obesity and the Pathogenesis of Barrett’s Esophagus -- Obesity and Pancreatic Cancer -- Obesity, Insulin Resistance Pathway Factors and Colon Cancer -- Ras/Raf and their Influence in Glycolysis in Colon Cancer -- Energy Balance and Other Modifiable Host Factors on Colorectal Cancer Prognosis -- Cyclooxygenase-2 and Chronic Inflammation:  Drivers of Colorectal Tumorigenesis -- Index.
520 _aThe gastrointestinal track provides one of the distinct systems where multiple malignancies, including adenocarcinoma of the pancreas, esophagus and colon are each associated with obesity. This unique association is covered in this volume of Energy Balance and Cancer from the epidemiologic, biologic and potential etiologic viewpoint. The focus on possible dietary contribution as well as the role of exercise in prevention and therapy is presented in both animal model and patient based studies. Special focus is provided also on the role of genetic mutations and inflammatory pathways as drivers of these obesity related gastrointestinal malignancies. Overall, this volume on Energy Balance and Gastrointestinal Malignancies should be valuable to Epidemiologists, Gastroenterologists and Oncologists, as well as to students and researchers from multiple disciplines interested in understanding and disrupting the association between obesity and cancer.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aHuman physiology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aHuman Physiology.
700 1 _aBerger, Nathan A.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461423669
830 0 _aEnergy Balance and Cancer ;
_v4
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-2367-6
912 _aZDB-2-SBL
999 _c101269
_d101269