000			03212nam a22004575i 4500
001			978-1-4614-2152-8
003			DE-He213
005			20140220083245.0
007			cr nn 008mamaa
008			130220s2012 xxu| s |||| 0|eng d
020			_a9781461421528 _9978-1-4614-2152-8
024	7		_a10.1007/978-1-4614-2152-8 _2doi
050		4	_aQH505
072		7	_aPHVN _2bicssc
072		7	_aPHVD _2bicssc
072		7	_aSCI009000 _2bisacsh
082	0	4	_a571.4 _223
100	1		_aJi, Sungchul. _eauthor.
245	1	0	_aMolecular Theory of the Living Cell _h[electronic resource] : _bConcepts, Molecular Mechanisms, and Biomedical Applications / _cby Sungchul Ji.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2012.
300			_aXXI, 748p. 237 illus., 129 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPart I Principles, Laws, and Concepts -- Physics -- Chemistry -- Biology -- Engineering -- Linguistics, Semiotics, and Philosophy -- Part II Theories, Molecular Mechanisms, and Models -- Molecular Mechanisms of Enzymic Catalysis -- The Conformon -- Intracellular Dissipative Structures (IDSs) -- The Living Cell -- Part III Applications: From Molecules to Mind and Evolution -- Subcellular Systems -- Whole Cells -- Mechanisms of the Origin of Life -- Principles and Mechanisms of Biological Evolution -- Multicellular Systems -- What Is Life?- Why Is the Cell So Complex?- Ribonoscopy and Personalized Medicine -- Ribonoscopy and ‘Theragnostics’ -- Application of the Knowledge Uncertainty Principle to Biomedical Sciences -- Conclusions.
520			_aThis book presents a comprehensive molecular theory of the living cell based on over thirty concepts, principles and laws imported from thermodynamics, statistical mechanics, quantum mechanics, chemical kinetics, informatics, computer science, linguistics, semiotics, and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for the basic living processes such as ligand-receptor interactions, protein folding, single-molecule enzymic catalysis, force-generating mechanisms in molecular motors, signal transduction, regulation of the genome-wide RNA metabolism, morphogenesis, the micro-macro coupling in coordination dynamics, the origin of life, and the mechanisms of biological evolution itself. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotheragnostics and personalized medicine.
650		0	_aPhysics.
650		0	_aBioorganic chemistry.
650		0	_aBiology _xPhilosophy.
650	1	4	_aPhysics.
650	2	4	_aBiophysics and Biological Physics.
650	2	4	_aBioorganic Chemistry.
650	2	4	_aPhilosophy of Biology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461421511
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-2152-8
912			_aZDB-2-PHA
999			_c101215 _d101215