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001 978-1-4614-0881-9
003 DE-He213
005 20140220083240.0
007 cr nn 008mamaa
008 111214s2012 xxu| s |||| 0|eng d
020 _a9781461408819
_9978-1-4614-0881-9
024 7 _a10.1007/978-1-4614-0881-9
_2doi
050 4 _aRM1-950
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
082 0 4 _a615
_223
100 1 _aSiepmann, Juergen.
_eeditor.
245 1 0 _aFundamentals and Applications of Controlled Release Drug Delivery
_h[electronic resource] /
_cedited by Juergen Siepmann, Ronald A. Siegel, Michael J. Rathbone.
264 1 _aBoston, MA :
_bSpringer US,
_c2012.
300 _aXIII, 592p. 156 illus., 33 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Delivery Science and Technology
505 0 _aThe Need for Drugs and Drug Delivery Systems -- Overview of Controlled Release Mechanisms -- Hydrophobic Polymers of Pharmaceutical Significance -- Hydrogels -- Biodegradable Polymers in Drug Delivery Systems -- Diffusion Controlled Drug Delivery Systems -- Swelling Controlled Drug Delivery Systems -- Degradable Polymeric Carriers for Parenteral Controlled Drug Delivery Systems -- Porous Systems -- Targeted Delivery Using Biodegradable polymeric Nanoparticles -- Liposomes in Drug Delivery -- Receptor Mediated Delivery Systems for Cancer Therapeutics -- Biological Rhythms, Drug Delivery, and Chronotherapeutics -- Site Specific Controlled Release for Cardiovascular Disease – Translational Direction -- Drug Delivery Systems to Fight Cancer -- Applications of  Vaccine Delivery in Infectious Diseases -- Tissue Engineering in Drug Delivery -- The Shaping of Controlled Release Drug Product Development by Emerging Trends in the Commercial, Regulatory and Political Macro-Environment.
520 _aThis authoritative book covers the fundamentals relating to the science and technology of drug delivery.  The book is written at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms.  It is a book that provides a simple encapsulation of concepts and expands on them using a building block approach to each subject, starting at a basic level and building to extend the readers knowledge and application of the subject.  In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material is introduced in order to build up the reader’s understanding and comprehension of the subject matter.   The book comprises several Parts.  The first part covers the fundamentals of drug delivery, the second covers delivery materials, the third deals with delivery systems (both temporal and spatial) and the fourth introduces the reader to some clinical applications of drug delivery. The book ends with a future outlook chapter in which prospects for the field are envisioned.   This book will be indispensible to scientists interested in the science and technology of drug delivery and be essential for those developing delivery systems designed to improve the clinical performance of a drug.   Professor Juergen Siepmann is Professor of Pharmaceutics at the College of Pharmacy, Université Lille Nord de France, Lille, France. He studied pharmacy and received his doctoral degree from the Freie Universitaet Berlin, Berlin, Germany, in 1999. His research focuses on the elucidation of the underlying mass transport phenomena in controlled drug delivery systems. Prof. Siepmann is reviews editor of the International Journal of Pharmaceutics and president of APGI (French Association of Pharmaceutical Technology). Since 2010 he is heading the INSERM (French National Institute of Health and Medical Research) research group “Controlled Drug Delivery Systems and Biomaterials”.     Ronald A. Siegel, Sc.D., is Professor of Pharmaceutics and Biomedical Engineering at the University of Minnesota.  He received his doctoral degree from MIT under the direction of Prof. Robert Langer in 1984, and taught at the University of California, San Francisco until 1998, when he moved to Minnesota.  Professor Siegel is Fellow of the Controlled Release Society (CRS), the American Association of Pharmaceutical Scientists, and the American Institute of Medical and Biological Engineering.  He was president of CRS from 1997-1998.  His present research interests include hydrogels, block polymers, microfabricated sensors and drug delivery systems, and mathematical modeling of transport.     Michael J. Rathbone is Associate Professor of Pharmaceutics at the School of Pharmacy, Griffith University, Australia.  Dr. Rathbone’s research interests are in the modified delivery of bioactives to the mouth, polymeric delivery systems and long acting veterinary drug delivery systems.  He is a Fellow of the Controlled Release Society (CRS) and received the CRS Distinguished Service Award in 2006.  He has edited or co-edited many books in the fields of modified release drug delivery, oral mucosal drug delivery and veterinary drug delivery.
650 0 _aMedicine.
650 0 _aToxicology.
650 0 _aPharmacy.
650 0 _aBiochemistry.
650 1 4 _aBiomedicine.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aBiochemistry, general.
650 2 4 _aPharmacy.
700 1 _aSiegel, Ronald A.
_eeditor.
700 1 _aRathbone, Michael J.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461408802
830 0 _aAdvances in Delivery Science and Technology
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-0881-9
912 _aZDB-2-SBL
999 _c100942
_d100942