000 02963nam a22004935i 4500
001 978-1-4614-0782-9
003 DE-He213
005 20140220083240.0
007 cr nn 008mamaa
008 111024s2012 xxu| s |||| 0|eng d
020 _a9781461407829
_9978-1-4614-0782-9
024 7 _a10.1007/978-1-4614-0782-9
_2doi
050 4 _aQH324.2-324.25
072 7 _aPSD
_2bicssc
072 7 _aUB
_2bicssc
072 7 _aSCI056000
_2bisacsh
082 0 4 _a570.285
_223
100 1 _aRodríguez-Ezpeleta, Naiara.
_eeditor.
245 1 0 _aBioinformatics for High Throughput Sequencing
_h[electronic resource] /
_cedited by Naiara Rodríguez-Ezpeleta, Michael Hackenberg, Ana M. Aransay.
264 1 _aNew York, NY :
_bSpringer New York,
_c2012.
300 _aXI, 255p. 29 illus., 25 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPreface -- Introduction -- Overview of Sequencing Technology Platforms -- Applications of High Throughput Sequencing -- Computational Infrastructure and Basic Data Analysis for High-Throughput Sequencing -- Base-Calling for Bioinformaticians -- De Novo Short Read Assembly -- Short Read Mapping -- DNA-Protein Interaction Analysis (ChIP-Seq) -- Genome-wide Methylation Maps -- Differential Expression for RNA Sequencing (RNA-seq) Data: Mapping, Summarization, Statistical Analysis and Experimental Design -- MicroRNA Expression Profiling and Discovery -- Dissecting Splicing-Regulatory Network by Integrative Analysis of HITS-CLIP data -- Analysis of Metagenomics Data -- High Throughput Sequencing Data Analysis Software: Current State and Future Developments -- Index.
520 _aThe ultimate goal of bioinformatics is to extract biological knowledge out of the large amount of information generated by the scientific community. The chapters compiled in this volume will allow both biologists and computer scientists to understand the significance and potential of this discipline in the analysis of high throughput sequencing data. An essential reference book, not only for serving as guideline for the comprehension of the main data analysis steps, but also for providing new insights into existing software and inspiration to develop new applications.
650 0 _aLife sciences.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aBioinformatics.
650 1 4 _aLife Sciences.
650 2 4 _aBioinformatics.
650 2 4 _aHuman Genetics.
650 2 4 _aBiomedicine general.
700 1 _aHackenberg, Michael.
_eeditor.
700 1 _aAransay, Ana M.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461407812
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-0782-9
912 _aZDB-2-SBL
999 _c100924
_d100924