000			03264nam a22004695i 4500
001			978-1-4614-0254-1
003			DE-He213
005			20140220083238.0
007			cr nn 008mamaa
008			130607s2012 xxu| s |||| 0|eng d
020			_a9781461402541 _9978-1-4614-0254-1
024	7		_a10.1007/978-1-4614-0254-1 _2doi
050		4	_aQH573-671
072		7	_aPSF _2bicssc
072		7	_aSCI049000 _2bisacsh
082	0	4	_a571.6 _223
100	1		_aRhim, Johng S. _eeditor.
245	1	0	_aHuman Cell Transformation _h[electronic resource] : _bRole of Stem Cells and the Microenvironment / _cedited by Johng S. Rhim, Richard Kremer.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2012.
300			_aXXII, 224p. 62 illus., 46 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v720
505	0		_aNuclear Barrier Hypothesis of Aging as Mechanism for Tradeoff Growth to Survival -- Establishment of Cell Lines from the Human Middle and Inner Ear Epithelial Cells -- Cellular Systems for Studying Human Oral Squamous Cell Carcinomas -- Heterotopic Ossification Following Musculoskeletal Trauma: Modeling Stem and Progenitor Cells in Their Microenvironment -- Comparative Proteomic Analysis of Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord, and Placenta: Implication in the Migration -- Novel Human Prostate Epithelial Cell Culture Models for the Study of Carcinogenesis and of Normal Stem Cells and Cancer Stem Cells -- Prostate Tumor Cell Plasticity: A Consequence of the Microenvironment -- Role of Epigenetics in Cancer Initiation and Progression -- Cancer Stem Cells, Models of Study and Implications of Therapy Resistance Mechanisms -- The Role of the Basal Stem Cell of the Human Breast in Normal Development and Cancer -- Breast Cancer Subtypes: Two Decades of Journey from Cell Culture to Patients -- Parathyroid Hormone Related Protein (PTHrP) in Tumor Progression -- Mechanism of Radiation Carcinogenesis: Role of the TGFBI Gene and The Inflammatory Signalling Cascade -- Histone Deacetylase Inhibitors: Anti-Neoplastic Agent and Radiation Modulator -- Human Fibroblasts for Large-Scale “Omics” Investigations of ATM Gene Function -- Malignant Transformation of Human Skin Fibroblasts by Two Alternative Pathways -- A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified By Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-Tumor Agent.
520			_aNo back cover text
650		0	_aLife sciences.
650		0	_aCytology.
650		0	_aStem cells.
650	1	4	_aLife Sciences.
650	2	4	_aCell Biology.
650	2	4	_aStem Cells.
700	1		_aKremer, Richard. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461402534
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v720
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-0254-1
912			_aZDB-2-SBL
999			_c100816 _d100816