000 04619nam a22005535i 4500
001 978-1-4614-0106-3
003 DE-He213
005 20140220083238.0
007 cr nn 008mamaa
008 110923s2012 xxu| s |||| 0|eng d
020 _a9781461401063
_9978-1-4614-0106-3
024 7 _a10.1007/978-1-4614-0106-3
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
100 1 _aLambris, John D.
_eeditor.
245 1 0 _aCurrent Topics in Innate Immunity II
_h[electronic resource] /
_cedited by John D. Lambris, George Hajishengallis.
250 _a1.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2012.
300 _aXVIII, 354 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v946
505 0 _aPentraxins in humoral innate immunity -- galectins as pattern recognition receptors: structure, function, and evolution -- the role of innate immunity in trafficking of hematopoietic stem cells – an emerging link between activation of complement cascade and chemotactic gradients of bioactive sphingolipids -- interaction of the microbiome with the innate immune response in chronic wounds -- keystone species and community service through manipulation of innate immunity -- a conserved host and pathogen site on immunoglobulins: structural and functional aspects -- advances in understanding the structure, function, and mechanism of the scin and efb families of staphylococcal immune evasion proteins -- granzyme b: a new crossroad of complement and apoptosis -- role of c3, c5 and anaphylatoxin receptors in acute lung injury and in sepsis -- complement mediated ocular angiogenesis -- platelets, complement, and contact activation: partners in inflammation and thrombosis -- nuclear factor-κb in immunity and inflammation: the treg and th17 connection -- function of act1 in il-17 family signaling and autoimmunity -- differential effect of inhibiting md-2 and cd14 on lps- versus whole e. coli bacteria-induced cytokine responses in human blood -- zebrafish: model for the study of inflammation and the innate immune response to infectious diseases -- monocyte-derived inflammatory dendritic cells in the granuloma during mycobacterial infection -- nk/dc crosstalk in anti-viral response -- innate-adaptive crosstalk: how dendritic cells shape immune responses in the cns -- nutritional immunity: homology modeling of nramp metal import.
520 _aMounting evidence in the past decade indicates that innate immunity mediates functions above and beyond first-line defense against infection. It is now appreciated that innate immune mechanisms are critically involved in the development of adaptive immunity and, moreover, the regulation of diverse physiological and homeostatic processes. The latter explains why deregulation of innate immunity may lead to pathological disorders that are not necessarily or directly related to host defense. This Volume compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells. This book is an excellent source of information for researchers and clinicians with interests in immunology, host-microbe interactions, and infectious and inflammatory diseases.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aToxicology.
650 0 _aMedical virology.
650 0 _aEmerging infectious diseases.
650 0 _aMicrobiology.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aMicrobiology.
650 2 4 _aInfectious Diseases.
650 2 4 _aVirology.
650 2 4 _aPharmacology/Toxicology.
700 1 _aHajishengallis, George.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461401056
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v946
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-0106-3
912 _aZDB-2-SBL
999 _c100804
_d100804