000 03996nam a22004695i 4500
001 978-1-4614-0016-5
003 DE-He213
005 20140220083237.0
007 cr nn 008mamaa
008 120213s2012 xxu| s |||| 0|eng d
020 _a9781461400165
_9978-1-4614-0016-5
024 7 _a10.1007/978-1-4614-0016-5
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aRobertson, Erle S.
_eeditor.
245 1 0 _aCancer Associated Viruses
_h[electronic resource] /
_cedited by Erle S. Robertson.
250 _a1.
264 1 _aBoston, MA :
_bSpringer US,
_c2012.
300 _aXXIII, 866 p. 125 illus., 68 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Cancer Research
505 0 _aIn Memoriam -- Preface.- Peyton Rous: A centennial tribute to the founding father of cancer virology -- Historical Perspectives of Viruses and Cancer.- Virus Mediated Cell Proliferation -- Viral Encoded Genes and Cancer -- Oncogenic Viruses and Cancer Transmission -- Overview of DNA Viruses and Cancer -- Herpesviruses and Cancer -- Lymphocryptoviruses- EBV and its role in human cancer -- LCV and RRV in nonhuman primates -- Rhadinoviruses – KSHV and associated malignancies -- RFHV and contribution to disease -- Murine herpesvirus 68 in Tumorigenesis -- Marek’s Disease Virus and T cell Lymphomas -- Polyoma Viruses and Cancer -- SV40 as a Model System for Cancer -- BK virus and Transformation -- JC virus and Transformation -- Merkel Cell Polyoma viruses -- Papilloma Viruses – HPV and BPV and Cancer.-and Cell proliferation -- Overview of Hepatitis Viruses and Cancer -- Hepadna Viruses - HBV and Hepatocellular Carcinomas -- Hepatitis C Virus and Hepatocellular Carcinomas.– Human and Animal Retroviruses: HIV-1 a Risk Factor for Malignancy -- HTLV-1 and Cell Proliferation -- HTLV-2 and Cell Proliferation -- Avian and Murine Retroviruses -- Rous Sarcoma Virus -- Mouse Mammary Tumor Viruses -- Jaagsiekte Sheep Retrovirus and Lung Cancer -- Small RNAs and their Role in Viral Mediated Cancers -- Immunodeficiency and Opportunistic Viral infections and Cancer -- Index.
520 _aThis volume constitutes a comprehensive review of the different aspects of tumor virology 100 years after the discovery of the Rous-sarcoma virus. Its aim is to bring a greater focus on the contributions of viral agents to the development of cancer, and to create an up to date compendium of the general molecular biology of these viruses,  their gene products, and targeted functions. The content of the book comprises general chapters which tie into the many aspects of cancer-related viruses and how they contribute to cell proliferation, the genes that are responsible for driving these cancers, and their mechanisms of transmission. The book also reviews the current knowledge on the molecular biology of large DNA viruses and describes the many different pathways through which they contribute to cell proliferation. Papilloma viruses and Adenoviruses, well known to be associated with invasive carcinomas, and hepatitis viruses, HTLV and retroviruses are also discussed. This volume is dedicated to  Baruch Blumberg, an outstanding scientist and recipient of the Nobel Prize for the discovery of the hepatitis B virus, who was also the author of one of the chapters.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aToxicology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aPharmacology/Toxicology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441999993
830 0 _aCurrent Cancer Research
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-0016-5
912 _aZDB-2-SME
999 _c100795
_d100795