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Nano-Bio Probe Design and Its Application for Biochemical Analysis [electronic resource] / by Bang-Ce Ye, Min Zhang, Bin-Cheng Yin.

By: Ye, Bang-Ce [author.].
Contributor(s): Zhang, Min [author.] | Yin, Bin-Cheng [author.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: SpringerBriefs in Molecular Science: Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2012Description: VIII, 77p. 22 illus., 19 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783642295430.Subject(s): Chemistry | Biochemical engineering | Biochemistry | Nanotechnology | Chemistry | Biochemical Engineering | Nanotechnology | Biochemistry, general | Nanoscale Science and TechnologyDDC classification: 660.63 Online resources: Click here to access online
Contents:
Introduction -- Nanomaterial-Enhanced Fluorescence Polarization and Its Application -- Versatile Graphene-Based Nano-Bio Probe Design and Its Appliction -- Metal Nanoparticles-Based Colorimetric Probe Design and Its Application -- Metal Nanoclusters-Based Luminescent Probe Design and Its Application.
In: Springer eBooksSummary: In this volume, Prof. Ye and his coworkers propose and review the concept of nano-bio probe design for biochemical analysis on the basis of their recent published works. A unique biochemical analysis technology based on fluorescence polarization enhanced by nanoparticles is described here with successful applications in environmental monitoring, rapid and sensitive sensing protease activity and high-throughput screening of inhibitors. Furthermore, they introduce a versatile molecular beacon (MB)-like probe for the multiplex sensing of targets such as sequence-specific DNA, protein, metal ions and small molecule compounds based on the self-assembled biomolecule-graphene conjugates. Besides, some colorimetric and luminescence probes utilizing metal nanoparticles for biochemical applications are also presented, such as chiral enantiomer discrimination and separation, environmental monitoring, clinic diagnosis and etc.
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Introduction -- Nanomaterial-Enhanced Fluorescence Polarization and Its Application -- Versatile Graphene-Based Nano-Bio Probe Design and Its Appliction -- Metal Nanoparticles-Based Colorimetric Probe Design and Its Application -- Metal Nanoclusters-Based Luminescent Probe Design and Its Application.

In this volume, Prof. Ye and his coworkers propose and review the concept of nano-bio probe design for biochemical analysis on the basis of their recent published works. A unique biochemical analysis technology based on fluorescence polarization enhanced by nanoparticles is described here with successful applications in environmental monitoring, rapid and sensitive sensing protease activity and high-throughput screening of inhibitors. Furthermore, they introduce a versatile molecular beacon (MB)-like probe for the multiplex sensing of targets such as sequence-specific DNA, protein, metal ions and small molecule compounds based on the self-assembled biomolecule-graphene conjugates. Besides, some colorimetric and luminescence probes utilizing metal nanoparticles for biochemical applications are also presented, such as chiral enantiomer discrimination and separation, environmental monitoring, clinic diagnosis and etc.

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