03499nam a22005295i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001600172072001700188072002300205082001500228100003100243245011200274264008200386300003600468336002600504337002600530338003600556347002400592490005700616505065200673520109101325650001502416650001402431650003102445650002902476650002402505650001802529650001502547650003002562650002502592650002102617650004002638650002902678700003402707710003402741773002002775776003602795830005702831856004802888912001402936999001902950978-3-642-13185-1DE-He21320140220084537.0cr nn 008mamaa100917s2010 gw | s |||| 0|eng d a97836421318519978-3-642-13185-17 a10.1007/978-3-642-13185-12doi 4aQD410-412.5 7aPNND2bicssc 7aSCI0130402bisacsh04a547.052231 aJaouen, Gérard.eeditor.10aMedicinal Organometallic Chemistryh[electronic resource] /cedited by Gérard Jaouen, Nils Metzler-Nolte. 1aBerlin, Heidelberg :bSpringer Berlin Heidelberg :bImprint: Springer,c2010. aXVIII, 294 p.bonline resource. atextbtxt2rdacontent acomputerbc2rdamedia aonline resourcebcr2rdacarrier atext filebPDF2rda1 aTopics in Organometallic Chemistry,x1436-6002 ;v320 aArsenic-Based Drugs: From Fowler’s Solution to Modern Anticancer Chemotherapy -- Activation Mechanisms for Organometallic Anticancer Complexes -- Organometallic Antitumour Agents with Alternative Modes of Action -- Ferrocene Functionalized Endocrine Modulators as Anticancer Agents -- Titanocenes: Cytotoxic and Anti-angiogenic Chemotherapy Against Advanced Renal-Cell Cancer -- Organometallics as Structural Scaffolds for Enzyme Inhibitor Design -- Bioorganometallic Chemistry and Malaria -- Biomedical Applications of Organometal–Peptide Conjugates -- Organometallic Radiopharmaceuticals -- Carbon Monoxide: An Essential Signalling Molecule. aContents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule. 0aChemistry. 0aOncology. 0aPharmaceutical technology. 0aBiochemical engineering. 0aChemistry, Organic. 0aBiochemistry.14aChemistry.24aOrganometallic Chemistry.24aMedicinal Chemistry.24aCancer Research.24aPharmaceutical Sciences/Technology.24aBiochemical Engineering.1 aMetzler-Nolte, Nils.eeditor.2 aSpringerLink (Online service)0 tSpringer eBooks08iPrinted edition:z9783642131844 0aTopics in Organometallic Chemistry,x1436-6002 ;v3240uhttp://dx.doi.org/10.1007/978-3-642-13185-1 aZDB-2-CMS c112203d112203