Basics -- Neuroanatomy and Cortical Landmarks -- Spatial Resolution of fMRI Techniques -- The Electrophysiological Background of the fMRI Signal -- High-Field fMRI -- Press Button Solutions -- Clinical Applications -- Preoperative Blood Oxygen Level Dependent (BOLD) functional Magnetic Resonance Imaging (fMRI) of Motor and Somatosensory Function -- The Functional Anatomy of Speech Processing: From Auditory Cortex to Speech Recognition and Speech Production -- Use of fMRI Language Lateralization for Quantitative Prediction of Naming and Verbal Memory Outcome in Left Temporal Lobe Epilepsy Surgery -- Mapping of Recovery from Poststroke Aphasia: Comparison of PET and fMRI -- Functional Magnetic Resonance-Guided Brain Tumor Resection -- Direct Cortical Stimulation and fMRI -- Imaging Epileptic Seizures Using fMRI -- Special Issues in fMRI-Studies Involving Children -- Multimodal Brain Mapping in Patients with Early Brain Lesions -- Combining Transcranial Magnetic Stimulation with (f)MRI -- Clinical Magnetoencephalography and fMRI.

Functional MRI (fMRI) and the basic method of BOLD imaging were introduced in 1993 by Seiji Ogawa. From very basic experiments, fMRI has evolved into a clinical application for daily routine brain imaging. There have been various improvements in both the imaging technique as such as well as in the statistical analysis. In this volume, experts in the field share their knowledge and point out possible technical barriers and problems explaining how to solve them. Starting from the very basics on the origin of the BOLD signal, the book covers technical issues, anatomical landmarks, presurgical applications, and special issues in various clinical fields. Other modalities for brain mapping such as PET, TMS, and MEG are also compared with fMRI. This book is intended to give a state-of-the-art overview and to serve as a reference and guide for clinical applications of fMRI.