Environmental Epigenomics in Health and Disease (Record no. 97970)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04175nam a22005175i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-642-36827-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220082906.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 130514s2013 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783642368271 |
| -- | 978-3-642-36827-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-642-36827-1 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RB155-155.8 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH431 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MFN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED107000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 611.01816 |
| Edition number | 23 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 599.935 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Jirtle, Randy L. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Environmental Epigenomics in Health and Disease |
| Medium | [electronic resource] : |
| Remainder of title | Epigenetics and Complex Diseases / |
| Statement of responsibility, etc | edited by Randy L. Jirtle, Frederick L. Tyson. |
| 264 #1 - | |
| -- | Berlin, Heidelberg : |
| -- | Springer Berlin Heidelberg : |
| -- | Imprint: Springer, |
| -- | 2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XIV, 339 p. 26 illus., 16 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Epigenetics and Human Health, |
| International Standard Serial Number | 2191-2262 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Preface -- Epigenetic programming of the brain -- Epigenetics and maternal brain evolution -- Social environment and DNA methylation: A mechanism for linking nurture and nature -- Sex differences in epigenetic programming of brain differentiation: Implications for mental health and disease -- Epigenetics and neurological disorders -- Phenotypic plasticity, pleiotropy, and the growth-first theory of imprinting -- The imprinted brain: How genes set the balance between autism and psychosis -- Epigenetics at the interface of genetics and environmental factors in autism -- Epigenomic and non-coding RNA regulation in addictive processes -- Epigenetic therapies in neurological diseases -- Epigenetics, nutrition, diabetes, and obesity -- Nutrition, histone epigenetic marks, and disease -- Chromatin switching and gene dynamics associated with type 2 diabetes -- Developmental epigenetic programming in diabetes and obesity -- Epigenetics and cancer -- Developmental reprogramming by environmental estrogens: How early life exposures affect cancer risk in adulthood.- Human cancer epigenetics -- Epigenetics and the law -- Legal and ethical implications of epigenetics -- Subject index. . |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The capacity of the epigenome to interpret both internal and external stimuli and alter expression programs is a critical component in normal development, aging, and disease pathogenesis. In the past decade, we have witnessed an explosion of unprecedented research on and support for epigenetics, epigenomics, and their interface with human health and disease. In this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, a number of leading investigators in the field of epigenetics discuss patterns of epigenomic modifications in normal cells, and how environmentally-induced changes in them are associated with disease pathogenesis. The authors comprehensively review the epigenetic adaptations that occur in human embryonic stem cells, as well as in differentiating cells and organs such as the brain when exposed to environmental factors, and discuss the legal and ethical implications of such alterations. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic programming. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Oncology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human Genetics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cancer Research. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tyson, Frederick L. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783642368264 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Epigenetics and Human Health, |
| -- | 2191-2262 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-642-36827-1 |
| 912 ## - | |
| -- | ZDB-2-SBL |
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