RNA Interference from Biology to Therapeutics (Record no. 95215)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03876nam a22004455i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4614-4744-3 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220082816.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 121026s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781461447443 |
| -- | 978-1-4614-4744-3 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4614-4744-3 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MBGR |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED000000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Howard, Kenneth A. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | RNA Interference from Biology to Therapeutics |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | edited by Kenneth A. Howard. |
| 264 #1 - | |
| -- | Boston, MA : |
| -- | Springer US : |
| -- | Imprint: Springer, |
| -- | 2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XV, 337 p. 46 illus., 35 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in Delivery Science and Technology, |
| International Standard Serial Number | 2192-6204 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | RNA Interference Pathways and Therapeutic Exploitation RNA Interference -- Synthetic Dicer-Substrate siRNAs as Triggers of RNA Interference -- The Role of MicroRNAs in Natural Tissue Development and Application in Regenerative Medicine -- Intracellular Delivery Considerations for RNAi Therapeutics -- Mucosal Delivery of RNAi Therapeutics -- Nanomedicines for Systemic Delivery of RNAi Therapeutics -- Lipidoids: A Combinatorial Approach to siRNA Delivery -- Polymeric Micelles for siRNA Delivery -- RNAi Therapeutic Delivery by Exosomes -- Aptamer-Mediated siRNA Targeting -- RNAi as Anti-Viral Therapy: The HIV-1 Case -- Genome-Wide RNAi Screen for Identification of Human Host Factors Crucial for Influenza Virus Replication -- The Application of microRNAs in Cancer Diagnostics -- Therapeutic Application of miRNAs in Cancer -- Clinical Development of an Inhalable Anti-RSV siRNA Treatment. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The Nobel Prize winning discovery that small interfering RNA can be utilised to control cellular gene expression has propelled the field of RNA interference (RNAi) to the forefront of biomedical science as a potential molecular medicine set to revolutionalise disease treatment. Harnessing the molecular mechanisms of RNAi and development of delivery technologies is crucial for its transformation into a therapeutic modality, this dependency is the focus of “RNA Interference from Biology to Therapeutics” that gives a comprehensive overview of RNAi biology and state-of-the-art delivery methods relevant to clinical translation of RNAi therapeutics. Key players and shapers in the fields of RNAi and delivery science have been assembled in a single volume to produce a truly unique interdisciplinary text, making it a “must-read” for both students and experts in, and at the interface of, RNAi, pharmaceutical science and medicine. An attractive feature is the “future perspectives” section within each chapter that allows global leaders the opportunity to express their views on the direction the field is moving. Topics covered in the book include miRNA biology and therapeutic exploitation, exosome delivery and clinical translation. “RNA Interference from Biology to Therapeutics” is an up-to-the-minute, highly informative and invaluable text for those actively involved or interested in this fascinating and high-impact field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmaceutical technology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine general. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmaceutical Sciences/Technology. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9781461447436 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in Delivery Science and Technology, |
| -- | 2192-6204 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-1-4614-4744-3 |
| 912 ## - | |
| -- | ZDB-2-SBL |
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