The Intervertebral Disc (Record no. 93654)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04615nam a22004815i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-7091-1535-0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220082524.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 130902s2014 au | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783709115350 |
| -- | 978-3-7091-1535-0 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-7091-1535-0 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RD701-811 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MNS |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED065000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 617.47 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shapiro, Irving M. |
| Relator term | editor. |
| 245 14 - TITLE STATEMENT | |
| Title | The Intervertebral Disc |
| Medium | [electronic resource] : |
| Remainder of title | Molecular and Structural Studies of the Disc in Health and Disease / |
| Statement of responsibility, etc | edited by Irving M. Shapiro, Makarand V. Risbud. |
| 264 #1 - | |
| -- | Vienna : |
| -- | Springer Vienna : |
| -- | Imprint: Springer, |
| -- | 2014. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | X, 446 p. 130 illus., 42 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Biomechanical and Molecular Studies of the Intervertebral Disc: Introduction to the Structure, Function and Comparative Anatomy of the Vertebrae and the Intervertebral Disc -- The Intervertebral Disc: Overview of Disc Mechanics -- Development of the Intervertebral Disc -- Proteoglycans of the Intervertebral Disc -- Collagen and Other Proteins of the Nucleus Pulposus, Annulus Fibrosus and Cartilage Endplates -- Microenvironmental Regulation of Cell Function and Extracellular Matrix Synthesis by Disc Cells -- The Effects of Mechanical Forces on Nucleus and Annulus Cells -- The Role of the ADAMTS Proteins in the Intervertebral Disc -- Intervertebral Disc Disease: Pathogenesis and Current Treatment Modalities: Epidemiology of Lumbar Disc Degeneration -- Genetic Basis of Intervertebral Disc Degeneration -- Pathogenesis of Intervertebral Disc Degeneration -- Imaging Modalities for Studying Disc Pathology -- Surgical Indications for Lumbar Degenerative Disease -- Spinal Motion Restoration Devices for the Degenerate Disc -- The Non-Surgical Treatment of Back Pain -- Back Pain and Disc Degeneration: Are They Linked?- Clinical Features and Pathobiology of Chordoma -- Models of Disc Disease and Biological Regeneration: Large Animal Models of Disc Degeneration -- Intervertebral Disc Herniation -- The Sand Rat (Psammomys obesus obesus) Model of Spontaneous, Age-Related Intervertebral Disc Generation -- Use of Knockout and Transgenic Mouse Models in Disc Research -- Intervertebral Disc Culture Models and Their Applications to Study Pathogenesis and Repair -- Use of Stem Cells to Regenerate the Disc -- Gene Therapy Approaches for Disc Regeneration -- Enhancing Disc Repair by Growth Factors and Other Modalities -- Tissue Engineering of the Disc. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The intervertebral disc is composed of a complex tissue that separates neighboring vertebrae, permits a wide range of motion, and cushions the high biomechanical forces on the spine. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, this is the only book in the past fifty years devoted entirely to the study of the intervertebral disc. The first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies for mitigating the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is dedicated to approaches that model normal development, and the elucidation of the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. This unique and authoritative book bridges the gap between the basic and clinical sciences; its target audience includes basic scientists, orthopedists, neurologists, rehabilitation and physical therapists, primary care physicians and chiropractors, while it also addresses the needs of graduate students, medical students, interns, fellows, and patients who suffer from disc-related pathologies. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosurgery. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Orthopedics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Orthopedic surgery. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Surgical Orthopedics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosurgery. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Orthopedics. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Risbud, Makarand V. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783709115343 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-7091-1535-0 |
| 912 ## - | |
| -- | ZDB-2-SME |
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