Nanotoxicology (Record no. 92293)

000 -LEADER
fixed length control field 05097nam a22005415i 4500
001 - CONTROL NUMBER
control field 978-1-4614-8993-1
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220082503.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 131024s2014 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461489931
-- 978-1-4614-8993-1
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4614-8993-1
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RM1-950
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMG
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED071000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Durán, Nelson.
Relator term editor.
245 10 - TITLE STATEMENT
Title Nanotoxicology
Medium [electronic resource] :
Remainder of title Materials, Methodologies, and Assessments /
Statement of responsibility, etc edited by Nelson Durán, Silvia S. Guterres, Oswaldo L. Alves.
264 #1 -
-- New York, NY :
-- Springer New York :
-- Imprint: Springer,
-- 2014.
300 ## - PHYSICAL DESCRIPTION
Extent XV, 411 p. 42 illus., 22 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
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-- rdamedia
338 ## -
-- online resource
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347 ## -
-- text file
-- PDF
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490 1# - SERIES STATEMENT
Series statement Nanomedicine and Nanotoxicology,
International Standard Serial Number 2194-0452
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Foreword -- Preface -- Chapter 1: Nanomaterials -- Chapter 2: Concepts and Methodology of Interaction of Carbon Nanostructures with Cellular Systems -- Chapter 3: Nanostability -- Chapter 4: Pharmacokinetics and Phamacodynamics of Nanomaterials -- Chapter 5: In Vitro Cytotoxicity Assays of Nanoparticles on Different Cell Lines -- Chapter 6: Carbon Nanotubes: From Synthesis to Genotoxicity -- Chapter 7: From Combinatorial Display Techniques to Microarray Technology: New Approaches to the Development and Toxicological Profiling of Targeted Nanomedicines -- Chapter 8: Genetic Studies on the Effects of Nanomaterials -- Chapter 9: Cellular Mechanisms in Nanomaterial Internalization, Intracellular Trafficking and Toxicity -- Chapter 10: Cytotoxicity and Genotoxicity of Solid Lipid Nanoparticles -- Chapter 11: Cytotoxicity and Genotoxicity of Biogenically Synthesized Silver Nanoparticles -- Chapter 12: Cytotoxicity and Genotoxicity of Iron Oxides Nanoparticles -- Chapter 13: Poloxamers as Drug-Delivery Systems: Physico-Chemical, Pharmaceutical And Toxicological Aspects -- Chapter 14: Polymeric Nanoparticles: In Vivo Toxicological Evaluation, Cardiotoxicity and Hepatotoxicity -- Chapter 15: Cyto,Geno and Ecotoxicity of Copper Nanoparticles -- Chapter 16: Accessing the Erythrocyte Toxicity of Nanomaterials: From Current Methods to Biomolecular Surface Chemistry Interactions -- Index.
520 ## - SUMMARY, ETC.
Summary, etc This book takes a systematic approach to nanotoxicology and the developing risk factors associated with  nanosized particles during manufacture and use of nanotechnology. Beginning with a detailed introduction to engineered nanostructures, the first part of the book presents concepts and definitions of nanomaterials from quantum dots to graphene to fullerenes, with detailed discussion of functionalization, stability, and medical and biological applications. The second part critically examines methodologies used to assess cytotoxicity and genotoxicity. Coverage includes interactions with blood (erythrocytes), combinatorial and microarray techniques, cellular mechanisms, and ecotoxicology assessments. Part three describes cases studies both in vitro and in vivo for specific nanomaterials including solid lipid nanoparticles and nanostructured lipid carriers and metallic nanoparticles and metallic oxides. New information is also presented on toxicological aspects of poloxamers and polymeric nanoparticles as drug carriers as well as size effects on cytotoxicity and genotoxicity. Didactic aspects are emphasized in all chapters, making the book suitable for a broad audience ranging from advanced undergraduate and graduate students to researchers in academia and industry. In all, Nanotoxicology: Materials, Methodologies, and Assessments will provide comprehensive insight into biological and environmental interactions with nanostructures. Provides an introduction to nanostructures actually in use Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Toxicology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanochemistry.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Environmental toxicology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanotechnology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmacology/Toxicology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanochemistry.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Ecotoxicology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanotechnology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanoscale Science and Technology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Guterres, Silvia S.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Alves, Oswaldo L.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781461489924
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Nanomedicine and Nanotoxicology,
-- 2194-0452
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4614-8993-1
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-- ZDB-2-SBL

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