The Microbiome and the Brain / (Record no. 131143)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05933cam a2200589Ki 4500 |
| 001 - CONTROL NUMBER | |
| control field | 9781351235709 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | FlBoTFG |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220509193148.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu---unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191207s2020 flu o 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | OCoLC-P |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | OCoLC-P |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781351235693 |
| -- | electronic book |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1351235699 |
| -- | electronic book |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781351235709 |
| -- | electronic book |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1351235702 |
| -- | electronic book |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781351235679 |
| -- | electronic book |
| -- | Mobipocket |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1351235672 |
| -- | electronic book |
| -- | Mobipocket |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781351235686 |
| -- | electronic book |
| -- | EPUB |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1351235680 |
| -- | electronic book |
| -- | EPUB |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 0815376723 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780815376729 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)1130037913 |
| Canceled/invalid control number | (OCoLC)1129981285 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC-P)1130037913 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP356.3 |
| Item number | .P47 2020 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 004000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 056000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 060000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJD |
| Source | bicssc |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.8042 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Perlmutter, David, |
| Dates associated with a name | 1954- |
| 245 14 - TITLE STATEMENT | |
| Title | The Microbiome and the Brain / |
| Statement of responsibility, etc | edited by David Perlmutter. |
| 264 #1 - | |
| -- | Boca Raton, FL : |
| -- | CRC Press, |
| -- | [2020] |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (233 p.) |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 500 ## - GENERAL NOTE | |
| General note | Description based upon print version of record. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cover; Half Title; Title Page; Copyright Page; Contents; Editor; List of Contributors; Introduction; Chapter 1: Assessing the Microbiome-Current and Future Technologies and Applications; Methods for Sequencing the Microbiome; 16S rRNA Sequencing; Shotgun Metagenomic Sequencing; Generating Data from Samples; Common Descriptive Analysis Techniques for Microbiome Data; Diversity Analysis; Relative Abundance Plots; Functional Genomics; Critical Appraisal of Microbiome Data; Simple, Community-Level Analyses-16S rRNA Sequencing; Detailed Metagenomic Analyses-Shotgun Metagenomic Sequencing |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Bacterial Toxins Breaking the Gut and Blood-Brain BarriersThe Role of LPS in the Breakdown of the Blood-Brain Barrier and the Induction of Pathology in the CNS; Correlation of Intestinal Bacterial LPS Antibody with Occludin/Zonulin, S100B and Aquaporin 4; Association of Gram-Negative Bacterial Molecules (LPS, BCdT) with Alzheimer's Disease (AD); Circulating Antibodies against Bacterial Toxins May Become Pathogenic in the Context of BBB Breakdown; Conclusion; References; Chapter 4: The Microbiome-Its Role in Neuroinflammation: The Autism Spectrum Disorder Paradigm |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cross Communication between Brain and Gastrointestinal System: The Gut-Brain AxisCombined Gut and Blood-Brain Barriers Defects; ASD as a Prototypical Example of Gut-Brain Axis Dysfunction; CONCLUSION; References; Chapter 5: Nutrition and the Microbiome-Implications for Autism Spectrum Disorder; Introduction; ASD and Microbiota; ASD and Microbial Metabolites; Gastrointestinal Symptoms and ASD; Nutritional Challenges in Children with ASD; Influence of Diet on Microbiota Composition; Interventions Targeting the Microbiota in ASD to Manage Symptoms |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Potential Role of Nutrition in the Microbiota-to-Brain Communication in ASDConclusions and Future Directions; References; Chapter 6: Alzheimer's Disease, the Microbiome, and 21st Century Medicine; Looking Forward; References; Chapter 7: Microbial Involvement in Alzheimer's Disease; Introduction: AD and Human Microbiome; Gut Microbiota and Alzheimer's; Impaired Microbiota and Alzheimer's; Human microbiome and risk factors of AD; Targeting Gut Microbiota for AD Interventions; Future Directions; Conclusions; References; Chapter 8: The Role of the Microbiome in Mood; INTRODUCTION |
| 500 ## - GENERAL NOTE | |
| General note | The Gut and its Microbiota |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer's disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer's disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality. |
| 588 ## - | |
| -- | OCLC-licensed vendor bibliographic record. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Alternative Medicine |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Neurology |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Nutrition |
| Source of heading or term | bisacsh |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Brain |
| General subdivision | Microbiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human body |
| General subdivision | Microbiology. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | Taylor & Francis |
| Uniform Resource Identifier | https://www.taylorfrancis.com/books/9781351235709 |
| 856 42 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | OCLC metadata license agreement |
| Uniform Resource Identifier | http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf |
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