Mechanosensitivity of the Heart (Record no. 113227)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05735nam a22005295i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-90-481-2850-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220084556.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 100301s2010 ne | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9789048128501 |
| -- | 978-90-481-2850-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-90-481-2850-1 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MBGR |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED000000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kamkin, Andre. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Mechanosensitivity of the Heart |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | edited by Andre Kamkin, Irina Kiseleva. |
| 264 #1 - | |
| -- | Dordrecht : |
| -- | Springer Netherlands, |
| -- | 2010. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XXXVII, 471p. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Mechanosensitivity in Cells and Tissues ; |
| Volume number/sequential designation | 3 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Molecular Mechanisms of Mechanotransduction in Cardiac Cells -- Titin and Titin-Associated Proteins in Myocardial Stress-Sensing and Mechanical Dysfunction -- Mechanical Stretch-Induced Reorganization of the Cytoskeleton and the Small GTPase Rac-1 in Cardiac Fibroblasts -- Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease -- Mechanical Stress Induces Cardiomyocyte Hypertrophy Through Agonist-Independent Activation of Angiotensin II Type 1 Receptor -- Mechanically Induced Potentials and Currents of the Cardiac Cells in Healthy and Diseased Myocardium -- Mechanostransduction in Cardiac and Stem-Cell Derived Cardiac Cells -- Stretch-Activated Channels in the Heart: Contribution to Cardiac Performance -- Effects of Applied Stretch on Native and Recombinant Cardiac Na+ Currents -- Mechanosensitive Alterations of Action Potentials and Membrane Currents in Healthy and Diseased Cardiomyocytes: Cardiac Tissue and Isolated Cell -- The Role of Mechanosensitive Fibroblasts in the Heart: Evidence from Acutely Isolated Single Cells, Cultured Cells and from Intracellular Microelectrode Recordings on Multicellular Preparations from Healthy and Diseased Cardiac Tissue -- Scanning Ion Conductance Microscopy for Imaging and Mechanosensitive Activation of Selected Areas of Live Cells -- Mechano-Electric Feedback in the Whole Heart and a Computer Simulation Study -- The Contribution of MEF to Electrical Heterogeneity and Arrhythmogenesis -- Mechanical Modulation of a Reentrant Arrhythmia: The Atrial Flutter Case -- Early Hypertrophic Signals After Myocardial Stretch. Role of Reactive Oxygen Species and the Sodium/Hydrogen Exchanger -- Stretch-Induced Inotropy in Atrial and Ventricular Myocardium -- Effects of Wall Stress on the Dynamics of Ventricular Fibrillation: A Computer Simulation Study of Mechanoelectric Feedback -- Electromechanical Modelling of Cardiac Tissue -- Arteries as a Source of Myogenic Contractile Activity: Ionic Mechanisms -- Specific Mechanotransduction Signaling Involved in Myogenic Responses of the Cerebral Arteries. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This book presents the latest findings in field of research of mechanosensitivity of the heart. The Volume focuses on molecular mechanisms of mechanotransduction in cardiac cells. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It highlights the role of cardiac stretch-activated channels and their contribution to cardiac performance. This book provides justification of scientific significance and potential for clinical applications of findings of fundamental investigations in the field of mechanosensitivity, which is stressed by description of reported increased sensitivity of cardiac cells to mechanical stress under various pathological conditions. It contains new insights into mechanoelectrical feedback on the level of the whole heart and results of experimental investigations of electromechanical properties of cardiac tissue. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the effects of mechanical stress on the heart are focused on several issues. The majority of studies investigate the effects of mechanical stimulation on mechanosensitive channels, as its primary target and interactive agent, and aim on description of downstream intracellular signaling pathways together with addressing general issues of biomechanics of the heart. Knowledge of biomechanics, and mechanisms which underlie it on molecular, cellular, tissue, organ and organism, is necessary for understanding of the normal functioning of living organisms and allows to predict changes, which arise due to alterations of their environment, and possibly will allow to develop new methods of artificial intervention. The book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human physiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cardiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biochemistry. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cytology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine general. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cell Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical Biochemistry. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human Physiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cardiology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kiseleva, Irina. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9789048128495 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Mechanosensitivity in Cells and Tissues ; |
| Volume number/sequential designation | 3 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-90-481-2850-1 |
| 912 ## - | |
| -- | ZDB-2-SBL |
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