Adverse Drug Reactions (Record no. 111321)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03678nam a22005415i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-642-00663-0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220084522.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 111227s2010 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783642006630 |
| -- | 978-3-642-00663-0 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-642-00663-0 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM1-950 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MMG |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED071000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Uetrecht, Jack. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Adverse Drug Reactions |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | edited by Jack Uetrecht. |
| 264 #1 - | |
| -- | Berlin, Heidelberg : |
| -- | Springer Berlin Heidelberg, |
| -- | 2010. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Handbook of Experimental Pharmacology, |
| International Standard Serial Number | 0171-2004 ; |
| Volume number/sequential designation | 196 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Target Organ Toxicity -- Drug-Induced Liver Injury -- Drug Hypersensitivity Reactions Involving Skin -- Adverse Drug Reactions Affecting Blood Cells -- Molecular Mechanisms of Adverse Drug Reactions in Cardiac Tissue -- Mechanisms of Drug-Induced Nephrotoxicity -- Receptor- and Reactive Intermediate-Mediated Mechanisms of Teratogenesis -- Mediators/Biochemical Pathways -- Role of Reactive Metabolites in Drug-Induced Hepatotoxicity -- The Role of Cytokines in the Mechanism of Adverse Drug Reactions -- The Keap1-Nrf2 Cellular Defense Pathway: Mechanisms of Regulation and Role in Protection Against Drug-Induced Toxicity -- Signal Transduction Pathways Involved in Drug-Induced Liver Injury -- Mitochondrial Involvement in Drug-Induced Liver Injury -- Examples/Models -- Mechanisms of Acetaminophen-Induced Liver Necrosis -- Drug-Induced Liver Injury in Humans: The Case of Ximelagatran -- Troglitazone -- Nevirapine Hypersensitivity -- Mechanisms of Adverse Drug Reactions to Biologics -- Risk Factors/Screening Drug Candidates -- Pharmacogenetics of Idiosyncratic Adverse Drug Reactions -- The Danger Hypothesis Applied to Idiosyncratic Drug Reactions -- Approaches for Minimizing Metabolic Activation of New Drug Candidates in Drug Discovery. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Allergy. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Dermatology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Clinical medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Public Health/Gesundheitswesen. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Hepatology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Dermatology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Allergology. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783642006623 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Handbook of Experimental Pharmacology, |
| -- | 0171-2004 ; |
| Volume number/sequential designation | 196 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-642-00663-0 |
| 912 ## - | |
| -- | ZDB-2-SBL |
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