Guidelines for Molecular Analysis in Archive Tissues (Record no. 107322)

000 -LEADER
fixed length control field 03439nam a22004455i 4500
001 - CONTROL NUMBER
control field 978-3-642-17890-0
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083752.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110606s2011 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783642178900
-- 978-3-642-17890-0
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-3-642-17890-0
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RB1-214
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMF
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED067000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.07
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Stanta, Giorgio.
Relator term editor.
245 10 - TITLE STATEMENT
Title Guidelines for Molecular Analysis in Archive Tissues
Medium [electronic resource] /
Statement of responsibility, etc edited by Giorgio Stanta.
264 #1 -
-- Berlin, Heidelberg :
-- Springer Berlin Heidelberg,
-- 2011.
300 ## - PHYSICAL DESCRIPTION
Extent XVI, 323p. 46 illus., 31 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Introduction -- Archive Tissues -- Pre-Analytical Treatment of Tissues -- Dissection of Tissue Components -- Extraction, Purification, Quantification and Quality Assessment of Nucleic Acids -- Reverse Transcription (RT) -- Nucleic Acid Amplification -- DNA Sequencing -- Microsatellite Analysis -- Methylation Analysis -- Analysis of Copy Number Variations -- Microarrays -- Protein Extraction in Archive Tissues -- Protein Electrophoretic Separation -- Protein Immunodetection -- Mass Spectrometry -- Elements of Good Laboratory Practice. -- DNA Sequencing -- Microsatellite Analysis -- Methylation Analysis -- Analysis of Copy Number Variations -- Microarrays -- Protein Extraction in Archive Tissues -- Protein Electrophoretic Separation -- Protein Immunodetection -- Mass Spectrometry -- Elements of Good Laboratory Practice.
520 ## - SUMMARY, ETC.
Summary, etc A huge amount of fixed and paraffin-embedded tissue is stored in every hospital. This is very precious material that can be used for translational research and for diagnostics. The molecular methods employed for analysis of these tissues are similar to the usual molecular biology and proteomics methods, but reliable results can be obtained only if specific steps are followed with great care.   This book provides detailed and precise guidelines for molecular analysis of archive tissues and will serve as an invaluable aid for researchers and pathologists involved in translational research and diagnostics. The topics addressed include pre-analytical treatment of tissues, isolation of tissue components, DNA and RNA methods, proteomics methods, internal quality control procedures, and storage and treatment of reagents. Clear notes and explanations are included to simplify use of the protocols for the less experienced. The authors are a group of acknowledged experts who have developed the described methods and validated them within the European project "Archive Tissues: Improving Molecular Medicine Research and Clinical Practice - IMPACTS", which has involved 21 leading institutions in 11 countries.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oncology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pathology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pathology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Molecular Medicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oncology.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783642178894
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-642-17890-0
912 ## -
-- ZDB-2-SME

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