Modeling in Systems Biology (Record no. 106489)

000 -LEADER
fixed length control field 05240nam a22004935i 4500
001 - CONTROL NUMBER
control field 978-1-84996-474-6
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083737.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 101029s2011 xxk| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781849964746
-- 978-1-84996-474-6
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-84996-474-6
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH324.2-324.25
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSA
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code UB
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code COM014000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 570.285
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Koch, Ina.
Relator term editor.
245 10 - TITLE STATEMENT
Title Modeling in Systems Biology
Medium [electronic resource] :
Remainder of title The Petri Net Approach /
Statement of responsibility, etc edited by Ina Koch, Wolfgang Reisig, Falk Schreiber.
264 #1 -
-- London :
-- Springer London :
-- Imprint: Springer,
-- 2011.
300 ## - PHYSICAL DESCRIPTION
Extent XXIV, 364 p.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
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-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Computational Biology,
International Standard Serial Number 1568-2684 ;
Volume number/sequential designation 16
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Part I: Foundations -- Introduction -- Biochemical Fundamentals -- Petri Nets -- Part II: Modeling Techniques -- Discrete Modeling -- Modeling Genetic Regulatory Networks -- Hybrid Functional Petri Net with Extension for Dynamic Pathway Modeling -- Stochastic Modeling -- Quantitative Analysis -- Fuzzy Modeling -- Part III: Biochemical Applications -- Topological Analysis of Metabolic and Regulatory Networks -- Analysis of Dynamical Models of Signaling Networks with Petri Nets and Dynamic Graphs -- A Modular, Qualitative Modeling of Regulatory Networks Using Petri Nets -- A Case Study of HFPN Simulation: Finding Essential Roles of Ror Gene in the Interaction of Feedback Loops in Mammalian Circadian Clock -- Prediction of Network Structure.
520 ## - SUMMARY, ETC.
Summary, etc The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive overview of cutting-edge research in applications of Petri nets in systems biology, with contributions from an international selection of experts. Those unfamiliar with the field are also provided with a general introduction to systems biology, the foundations of biochemistry, and the basics of Petri net theory. Further chapters address Petri net modeling techniques for building and analyzing biological models, as well as network prediction approaches, before reviewing the applications to networks of different biological classification. Topics and features: Investigates the modular, qualitative modeling of regulatory networks using Petri nets, and examines an Hybrid Functional Petri net simulation case study Contains a glossary of the concepts and notation used in the book, in addition to exercises at the end of each chapter Covers the topological analysis of metabolic and regulatory networks, the analysis of models of signaling networks, and the prediction of network structure Provides a biological case study on the conversion of logical networks into Petri nets Discusses discrete modeling, stochastic modeling, fuzzy modeling, dynamic pathway modeling, genetic regulatory network modeling, and quantitative analysis techniques Includes a Foreword by Professor Jens Reich, Professor of Bioinformatics at Humboldt University and Max Delbrück Center for Molecular Medicine in Berlin This unique guide to the modeling of biochemical systems using Petri net concepts will be of real utility to researchers and students of computational biology, systems biology, bioinformatics, computer science, and biochemistry. Dr. Ina Koch is a Professor and holds the Chair of Bioinformatics at the Johann Wolfgang Goethe-University Frankfurt am Main, Germany. Dr. Wolfgang Reisig is a Professor and holds the Chair in the Theory of Programming at the Humboldt University of Berlin, Germany. Dr. Falk Schreiber is a Professor and holds the Chair of Bioinformatics at the Martin Luther University Halle-Wittenberg, Germany, and the Coordinator of Bioinformatics at the Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben, Germany.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Computer science.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Bioinformatics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biological models.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Computer Science.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Computational Biology/Bioinformatics.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Systems Biology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Reisig, Wolfgang.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schreiber, Falk.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781849964739
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Computational Biology,
-- 1568-2684 ;
Volume number/sequential designation 16
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-84996-474-6
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