The Nucleolus (Record no. 106257)

000 -LEADER
fixed length control field 04160nam a22005295i 4500
001 - CONTROL NUMBER
control field 978-1-4614-0514-6
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083732.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110907s2011 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461405146
-- 978-1-4614-0514-6
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4614-0514-6
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH573-671
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSF
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI049000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 571.6
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Olson, Mark O. J.
Relator term editor.
245 14 - TITLE STATEMENT
Title The Nucleolus
Medium [electronic resource] /
Statement of responsibility, etc edited by Mark O. J. Olson.
264 #1 -
-- New York, NY :
-- Springer New York,
-- 2011.
300 ## - PHYSICAL DESCRIPTION
Extent XXVI, 414 p.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
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-- computer
-- c
-- rdamedia
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-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Protein Reviews ;
Volume number/sequential designation 15
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Nucleolar Structure and Organization.Structural organization of the nucleolus as a consequence of the dynamics of ribosome biogenesis.The dynamic  proteome of the nucleolus.The Structure of rDNA Chromatin.The epigenetics of the nucleolus: structure and function of active and silent ribosomal RNA genes.UBF, an Essential Player in Maintenance of Active NORs and nucleolar formation -- Role of the Nucleolus in Ribosome Biogenesis.The RNA Polymerase I Transcription Machinery.Small Ribonucleoproteins in Ribosome Biogenesis.Crosstalk between ribosome synthesis and cell cycle progression and its potential implications in  human genetic disease.The multiple properties and functions of nucleolin.The multifunctional nucleolar protein nucleophosmin/NPM/B23 and the nucleoplasmin family of proteins.Structure and function of NOPP140 and treacle -- Novel Functions of the Nucleolus.The Role of the Nucleolus in the Stress Response.New Frontiers in Nucleolar Research - Nucleostemin and Related Proteins.Viruses and the Nucleolus.Assembly of Signal Recognition Particles in the Nucleolus.Relationship of the Cajal Body to the Nucleolus.Role of the Nucleolus in HIV Infection and Therapy.
520 ## - SUMMARY, ETC.
Summary, etc Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest.  These new discoveries include not only the novel functions of the nucleouls, but also numerous breakthroughs on its conventional role.  Consequently, a large part of this volume is devoted to traditional functions of the nucleolus.  Recent research has led to so much information that the subject cannot be fully contained within one volume, so this book has focused on recent progress in specialized topics within the general subject. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.  Proteomics has shown that there are hundreds of proteins of unknown function in the nucleolus, which are likely to keep researchers busy for years.  In addition, the roles of many viral components in the nucleolus will continue to intrigue us, hopefully moving beyond the phenomenology that is now the case with many viral components in the nucleolus.  Even now, there is already evidence that we can take advantage of our knowledge of the nucleolus to develop therapeutic strategies, and this book hopes to help build the path to a new era of nucleolar translational medical research.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life sciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medical genetics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nucleic acids.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cytology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life Sciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cell Biology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Protein Science.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nucleic Acid Chemistry.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry, general.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oxidative Stress.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Gene Function.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781461405139
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Protein Reviews ;
Volume number/sequential designation 15
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4614-0514-6
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