Genes and Cardiovascular Function (Record no. 105710)

000 -LEADER
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001 - CONTROL NUMBER
control field 978-1-4419-7207-1
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083722.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110727s2011 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781441972071
-- 978-1-4419-7207-1
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4419-7207-1
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC681-688.2
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJD
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED010000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.12
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Ostadal, Bohuslav.
Relator term editor.
245 10 - TITLE STATEMENT
Title Genes and Cardiovascular Function
Medium [electronic resource] /
Statement of responsibility, etc edited by Bohuslav Ostadal, Makoto Nagano, Naranjan S. Dhalla.
264 #1 -
-- Boston, MA :
-- Springer US,
-- 2011.
300 ## - PHYSICAL DESCRIPTION
Extent XVI, 264p. 59 illus., 32 illus. in color.
Other physical details online resource.
336 ## -
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-- txt
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-- computer
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-- rdamedia
338 ## -
-- online resource
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347 ## -
-- text file
-- PDF
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505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Johann Gregor Mendel “Father of modern genetics” -- Gene therapy: hopes and problems -- VEGFs, FGFs and PDGF coordinate embryonic coronary vascularization -- The E2F pathway in cardiac development and disease -- Cardiac sodium-calcium exchanger expression -- Scleraxis: a new regulator of extracellular matrix formation -- Gender impact on pathophysiology of the heart -- Mitochondrial DNA and heart disease -- A novel algorithm from personal genome to the pathogenic mutant causing      mitochondrial cardiomyopathy -- MELAS Syndrome: mediated by impaired taurinomethyluridine synthesis -- Genetics of myocardial infarction -- Genetic background of myocardial infarction -- I/D ACE polymorphism and cardiovascular risk: disclosed story -- PPARs and myocardial response to ischemia in normal and diseased heart -- Genes and plasma lipids in Czech Slavic population -- Genetic basis of salt-sensitive hypertension in humans -- Gene-environment interactions: their role in hypertension development -- Phenotypic overlap of lethal arrhythmias associated with cardiac sodium mutations: Individual-specific or mutation-specific? -- CLP-1 mediated transcriptional control of hypertrophic gene programs underlying cardiac hypertrophy -- Molecular mechanisms of subcellular remodeling in congestive heart failure -- Cardiomyopathy, sarcomeropathy and Z-discopathy -- Left ventricular assist device: morphological, molecular and genetic changes after  mechanical support -- Vascular Ehlers-Danlos syndrome: a good experimental model is needed for development of treatment strategies -- Multi-scale, multi-physics heart simulator as a tool to link bench and bedside.
520 ## - SUMMARY, ETC.
Summary, etc Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology.  In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression.  The ability to rapidly identify candidate human genes for cardiovascular diseases lends itself to the development of diverse strategies for disease treatment and management.  The wide variety of gene expressions proffers excellent targets for novel therapeutics.  Gene therapy is steadily increasing in viability and represents a fascinating arena of research and clinical focus.   This book is based on two international Mendel symposia on “Genes and the Heart,” joint meetings of the Japanese and European sections of the International Academy of Cardiovascular Sciences.  Highlighting selected symposia contributions, this book explores the role of molecular biology and genetics in the basic knowledge, genesis, and clinical interventions of cardiovascular diseases.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cardiology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cardiology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medical Biochemistry.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Nagano, Makoto.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dhalla, Naranjan S.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781441972064
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4419-7207-1
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