Stem Cells and Human Diseases (Record no. 104572)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 05119nam a22004695i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-94-007-2801-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220083343.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120130s2012 ne | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9789400728011 |
| -- | 978-94-007-2801-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-94-007-2801-1 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MBGR |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED000000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Srivastava, Rakesh. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Stem Cells and Human Diseases |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | edited by Rakesh Srivastava, Sharmila Shankar. |
| 264 #1 - | |
| -- | Dordrecht : |
| -- | Springer Netherlands, |
| -- | 2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | IX, 630p. 76 illus., 44 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. Cancer Stem Cells: Biology, Perspectives and Therapeutic Implications -- 2. The Perspectives of Stem Cell-based Therapy in Neurological Diseases -- 3. Stem Cell-based Therapy for Lysosomal Storage Diseases -- 4. Drosophila germline stem cells -- 5. Mesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation -- 6. Cancer Stem Cells in Solid Tumors, Markers and Therapy -- 7. Cancer Stem Cells: Paradigm Shifting or Perishing Concept -- 8. Genomics of Prostate Cancer -- 9. Ischemia, reactive radicals, redox signaling and hematopoietic stem cells -- 10. Cancer stem cell models and role in drug discovery -- 11. Origins of Metastasis-Initiating Cells -- 12. The Reduction of Callus Formation during Bone Regeneration by BMP-2 and Human Adipose Derived Stem Cells -- 13. Stem cells and leukemia -- 14. The role of adult bone marrow derived mesenchymal stem cells, growth factors and scaffolds in the repair of cartilage and bone -- 15. Worth the Weight: Adipose Stem Cells in Human Disease -- 16. Neural crest and Hirschsprung’s disease -- 17. Common denominators of self-renewal and malignancy IN neural stem cells and GLIOMA -- 18. Stem-like cells from brain tumours or vice versa? -- 19. Translating Mammary Stem Cell and Cancer Stem Cell Biology to the Clinics -- 20. Breast Cancer Stem Cells -- 21. Translin/TRAX deficiency affects mesenchymal differentiation programs and induces bone marrow failure -- 22. Cancer therapies and Stem cells -- 23. Cancer Stem Cells and Head and Neck Squamous Cell Carcinomas -- 24. The Biology of Lung Cancer Stem Cells -- 25. Stem Cell Characters in Primary and Metastatic Tumour Establishment -- 26. Plasticity of Cancer Stem Cells -- 27. Cross talks among Notch, Wnt, and Hedgehog signaling pathways regulate stem cell characteristics -- 28. Global OMICs profiling and functional analysis of CD44+/CD24- stem-like cells in normal human breast tissue and breast cancer -- 29. Breast Cancer Stem Cells: Isolation, characterization and targeting. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | There have been major advances in understanding the behavior of stem cells and their roles in tissue regeneration, homeostasis and therapy. Cancer stem cell hypothesis opened a new opportunity for treating and preventing cancers by targeting cancer stem cells or cancer initiating cells. An increased understanding of stem cell behavior and biology along with rapid advancement of high throughput screening has led to the discovery and development of novel drugs that control stem cell self-renewal and differentiation. In near future, these molecules will be very useful for treating and preventing several human diseases. While progress on the clinical front has been slower than desired, the use of stem cells for tissue regeneration and disease management has great potential in human health. The first decade of the 21st century has brought with it significant progress in our understanding of stem cell or progenitor cells and their role in tissue regeneration and management of human diseases including cancer, neurodegenerative disorders, and heart diseases. This book covers the current state-of-the-art knowledge on the role of stem cells in tissue regeneration, homeostasis and disease management. Features: Coverage of the biology of stem cell and their role in tissue regeneration and organogenesis. Mechanism-based strategies for stem cell self-renewal and differentiation. Role of cancer stem cells or tumor initiating cells in cancer initiation, progression, relapse and drug resistance. Use of stem cells in treating several human diseases, such as Alzheimer’s disease, Parkinson’s disease, cancer and diabetes. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Entomology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Literacy. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine general. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Literacy. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine/Public Health, general. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Entomology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shankar, Sharmila. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9789400728004 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-94-007-2801-1 |
| 912 ## - | |
| -- | ZDB-2-SBL |
No items available.